X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910 : agreement of time-resolved spectroscopy and molecular dynamics simulations

S. Ringhofer; J. Kallen; R. Dutzler; A. Bilich; A.J.W.G. Visser; D. Scholz; O. Steinhauser; H. Schreiber; M. Auer; A.J. Kungl

X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910 : agreement of time-resolved spectroscopy and molecular dynamics simulations

S. Ringhofer, J. Kallen, R. Dutzler, A. Bilich, A.J.W.G. Visser, D. Scholz, O. Steinhauser, H. Schreiber, M. Auer, A.J. Kungl

Biochemistry

Research output: Contribution to journal › Article › Academic › peer-review

26 Citations (Scopus)

Original language	English
Pages (from-to)	1147-1159
Journal	Journal of Molecular Biology
Volume	286
Publication status	Published - 1999

Keywords

AIDS
HIV-1 protease
Molecular dynamics
Time-resolved fluorescence
X-ray crystallography

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

Ringhofer, S., Kallen, J., Dutzler, R., Bilich, A., Visser, A. J. W. G., Scholz, D., Steinhauser, O., Schreiber, H., Auer, M., & Kungl, A. J. (1999). X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910 : agreement of time-resolved spectroscopy and molecular dynamics simulations. Journal of Molecular Biology, 286, 1147-1159.

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title = "X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910 : agreement of time-resolved spectroscopy and molecular dynamics simulations",

keywords = "AIDS, HIV-1 protease, Molecular dynamics, Time-resolved fluorescence, X-ray crystallography",

author = "S. Ringhofer and J. Kallen and R. Dutzler and A. Bilich and A.J.W.G. Visser and D. Scholz and O. Steinhauser and H. Schreiber and M. Auer and A.J. Kungl",

year = "1999",

language = "English",

volume = "286",

pages = "1147--1159",

journal = "Journal of Molecular Biology",

issn = "0022-2836",

publisher = "Elsevier",

}

Ringhofer, S, Kallen, J, Dutzler, R, Bilich, A, Visser, AJWG, Scholz, D, Steinhauser, O, Schreiber, H, Auer, M & Kungl, AJ 1999, 'X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910 : agreement of time-resolved spectroscopy and molecular dynamics simulations', Journal of Molecular Biology, vol. 286, pp. 1147-1159.

X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910 : agreement of time-resolved spectroscopy and molecular dynamics simulations. / Ringhofer, S.; Kallen, J.; Dutzler, R. et al.
In: Journal of Molecular Biology, Vol. 286, 1999, p. 1147-1159.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910 : agreement of time-resolved spectroscopy and molecular dynamics simulations

AU - Ringhofer, S.

AU - Kallen, J.

AU - Dutzler, R.

AU - Bilich, A.

AU - Visser, A.J.W.G.

AU - Scholz, D.

AU - Steinhauser, O.

AU - Schreiber, H.

AU - Auer, M.

AU - Kungl, A.J.

PY - 1999

Y1 - 1999

KW - AIDS

KW - HIV-1 protease

KW - Molecular dynamics

KW - Time-resolved fluorescence

KW - X-ray crystallography

M3 - Article

SN - 0022-2836

VL - 286

SP - 1147

EP - 1159

JO - Journal of Molecular Biology

JF - Journal of Molecular Biology

ER -