Why do polyunsaturated fatty acids lower serum cholesterol?

A.C. Beynen, M.B. Katan

Research output: Contribution to journalArticleAcademicpeer-review

82 Citations (Scopus)

Abstract

Replacement of saturated by polyunsaturated fatty acids in the diet may lower serum very low-density and low-density lipoprotein concentrations because the liver preferentially converts polyunsaturated fatty acids into ketone bodies instead of into very low-density lipoprotein triglycerides. Thus unlike saturated fatty acids, polyunsaturated fatty acids are transported to the tissues for oxidation without leaving a trail of lipoprotein remnants in the form of low-density lipoproteins.
Original languageEnglish
Pages (from-to)560-563
JournalAmerican Journal of Clinical Nutrition
Volume42
Issue number3
DOIs
Publication statusPublished - 1985

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