Whole genome scan in chickens for quantitative trait loci affecting carcass traits

J.B.C.H.M. van Kaam, M.A.M. Groenen, H. Bovenhuis, A. Veenendaal, A.L.J. Vereijken, J.A.M. van Arendonk

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An experiment was conducted to enable quantitative trait loci (QTL) mapping for carcass traits. The population consisted of 10 full-sib families originating from a cross between male and female founders chosen from two different outcross broiler lines. Founder animals, parents, offspring, and grandoffspring are denoted as generation (G) 0, 1, 2, and 3 animals, respectively. Microsatellite marker genotypes were collected on G1 and G2 animals. Phenotypic observations were collected on G3 animals. Recorded traits were BW at 48 d, carcass weight, carcass percentage, breast meat color, and leg score. Average adjusted progeny trait values were calculated for each G2 animal and for each trait after adjusting phenotypic observations on G3 animals for fixed effects, covariables, the additive genetic contribution of the other parent, and differences between sexes. The average adjusted progeny trait values were used as the dependent variable in the QTL analysis. A QTL analysis was undertaken by modeling the segregation from G1 to G2, using a full-sib across family regression interval mapping approach. In total, 27 autosomal linkage groups covered with 420 markers were analyzed. Genomewise significance thresholds were derived using the permutation test and a Bonferroni correction. Two QTL, affecting two of the five analyzed traits, exceeded suggestive linkage. The most significant QTL was located on Chromosome 1 at 466 cM and showed an effect on carcass percentage. The other QTL, which affected meat color, was located on Chromosome 2 and gave a peak at 345 and 369 cM.
Original languageEnglish
Pages (from-to)1091-1099
JournalPoultry Science
Issue number8
Publication statusPublished - 1999

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