TY - JOUR
T1 - Weight Loss in Patients with Dementia
T2 - Considering the Potential Impact of Pharmacotherapy
AU - Franx, Bart A.A.
AU - Arnoldussen, Ilse A.C.
AU - Kiliaan, Amanda J.
AU - Gustafson, Deborah R.
PY - 2017/6
Y1 - 2017/6
N2 - Unintentional body weight loss is common in patients with dementia and is linked to cognitive impairment and poorer disease outcomes. It is proposed that some dementia medications with market approval, while aiming to improve cognitive and functional outcomes of a patient with dementia, are associated with reported body weight or body mass index loss. This review presents evidence in the published literature on body weight loss in dementia, describes selected theories behind body weight loss, evaluates the potential impact of approved dementia pharmacotherapies on body weight, considers the potential role for medical foods, understands the potential influence of treatments for neuropsychiatric symptoms and signs, and finally, summarizes this important area.
AB - Unintentional body weight loss is common in patients with dementia and is linked to cognitive impairment and poorer disease outcomes. It is proposed that some dementia medications with market approval, while aiming to improve cognitive and functional outcomes of a patient with dementia, are associated with reported body weight or body mass index loss. This review presents evidence in the published literature on body weight loss in dementia, describes selected theories behind body weight loss, evaluates the potential impact of approved dementia pharmacotherapies on body weight, considers the potential role for medical foods, understands the potential influence of treatments for neuropsychiatric symptoms and signs, and finally, summarizes this important area.
U2 - 10.1007/s40266-017-0462-x
DO - 10.1007/s40266-017-0462-x
M3 - Article
C2 - 28478593
AN - SCOPUS:85027878619
SN - 1170-229X
VL - 34
SP - 425
EP - 436
JO - Drugs and Aging
JF - Drugs and Aging
IS - 6
ER -