Validation of an automated screening method for persistent organic contaminants in fats and oils by GC × GC-ToFMS

Patricia Lopez Sanchez, Marc Tienstra, Arjen Lommen, Hans G.J. Mol

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Abstract

An screening method, comprised of straightforward sample treatment based on silica clean-up, GC × GC-ToFMS detection and automated data processing with the non-proprietary free downloadable software MetAlignID, has been successfully validated with respect to false negatives for the sum PCB 28, 52, 101, 138, 153 and 180), for the sum of BDE 28, 47, 99, 100, 153, 154 and 183, for the four markers of PAHs and for a number of emerging brominated flame retardants. A screening detection limit (SDL) equal to or lower than the maximum regulatory level was always achieved. MetAlignID considerably decreased the time needed for data treatment from 20 to 5 min/file. Automated identification of the signature mass spectral patterns was applied to identify chlorinated- and brominated-containing substances with more than two halogen atoms, and PAH derivates. Although the success rate was variable and needs to be further improved, the tool was considered to be of added value.

Original languageEnglish
Pages (from-to)645-653
JournalFood Chemistry
Volume211
DOIs
Publication statusPublished - 2016

Keywords

  • Fat
  • GC × GC-ToFMS
  • Qualitative analysis
  • Screening
  • Validation

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