Urinary Iodine Concentrations Indicate Iodine Deficiency in Pregnant Thai Women but Iodine Sufficiency in Their School-Aged Children

S. Gowachirapant, P. Winichagoon, L. Wyss, B. Tong, J. Baumgartner, A. Boonstra, M.B. Zimmermann

Research output: Contribution to journalArticleAcademicpeer-review

66 Citations (Scopus)

Abstract

The median urinary iodine concentration (UI) in school-aged children is recommended for assessment of iodine nutrition in populations. If the median UI is adequate in school-aged children, it is usually assumed iodine intakes are also adequate in the remaining population, including pregnant women. But iodine requirements sharply increase during pregnancy. In this study, our aim was to measure UI in pairs of pregnant women and their school-aged children from the same family, who were sharing meals, to directly assess whether a household food basket that supplies adequate iodine to school-aged children also meets the needs of pregnant women. UI was measured in spot urine samples from pairs (n = 302) of healthy pregnant mothers and their school-aged children in metropolitan Bangkok, Thailand. A dietary questionnaire was completed. The UI [median (range)] in the pregnant women (108 (11-558) mu g/L [0.85 (0.086-4.41) mu mol/L]) were lower than those of their school-aged children (200 (25-835) mu g/L [1.58 (0.20-6.52) mu mol/L]) (P <0.001), indicating optimal iodine status in the children but mild-to-moderate iodine deficiency in their pregnant mothers. The estimated iodine intakes in the 2 groups were in the range of 130-170 mu g/d. There was a modest positive correlation between UI in the pairs (r = 0.253; P <0.01). A higher frequency of seafood meals was a significant predictor of UI in both groups, but household use of iodized salt was not. These data suggest the median UI in school-aged children should not be used as a surrogate for monitoring iodine status in pregnancy in central Thailand; pregnant women should be directly monitored
Original languageEnglish
Pages (from-to)1169-1172
JournalThe Journal of Nutrition
Volume139
Issue number6
DOIs
Publication statusPublished - 2009

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Iodine
Pregnant Women
Thailand
Meals
Mothers
Pregnancy
Seafood
Nutrition Assessment
Food Supply
Population

Keywords

  • universal salt iodization
  • nutrition
  • schoolchildren
  • cognition
  • excretion
  • area

Cite this

Gowachirapant, S. ; Winichagoon, P. ; Wyss, L. ; Tong, B. ; Baumgartner, J. ; Boonstra, A. ; Zimmermann, M.B. / Urinary Iodine Concentrations Indicate Iodine Deficiency in Pregnant Thai Women but Iodine Sufficiency in Their School-Aged Children. In: The Journal of Nutrition. 2009 ; Vol. 139, No. 6. pp. 1169-1172.
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abstract = "The median urinary iodine concentration (UI) in school-aged children is recommended for assessment of iodine nutrition in populations. If the median UI is adequate in school-aged children, it is usually assumed iodine intakes are also adequate in the remaining population, including pregnant women. But iodine requirements sharply increase during pregnancy. In this study, our aim was to measure UI in pairs of pregnant women and their school-aged children from the same family, who were sharing meals, to directly assess whether a household food basket that supplies adequate iodine to school-aged children also meets the needs of pregnant women. UI was measured in spot urine samples from pairs (n = 302) of healthy pregnant mothers and their school-aged children in metropolitan Bangkok, Thailand. A dietary questionnaire was completed. The UI [median (range)] in the pregnant women (108 (11-558) mu g/L [0.85 (0.086-4.41) mu mol/L]) were lower than those of their school-aged children (200 (25-835) mu g/L [1.58 (0.20-6.52) mu mol/L]) (P <0.001), indicating optimal iodine status in the children but mild-to-moderate iodine deficiency in their pregnant mothers. The estimated iodine intakes in the 2 groups were in the range of 130-170 mu g/d. There was a modest positive correlation between UI in the pairs (r = 0.253; P <0.01). A higher frequency of seafood meals was a significant predictor of UI in both groups, but household use of iodized salt was not. These data suggest the median UI in school-aged children should not be used as a surrogate for monitoring iodine status in pregnancy in central Thailand; pregnant women should be directly monitored",
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Urinary Iodine Concentrations Indicate Iodine Deficiency in Pregnant Thai Women but Iodine Sufficiency in Their School-Aged Children. / Gowachirapant, S.; Winichagoon, P.; Wyss, L.; Tong, B.; Baumgartner, J.; Boonstra, A.; Zimmermann, M.B.

In: The Journal of Nutrition, Vol. 139, No. 6, 2009, p. 1169-1172.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Winichagoon, P.

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AU - Tong, B.

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