Two for all: receptor-associated kinases SOBIR1 and BAK1

T.W.H. Liebrand, H.A. van den Burg, M.H.A.J. Joosten

Research output: Contribution to journalArticleAcademicpeer-review

146 Citations (Scopus)

Abstract

Leucine-rich repeat-receptor-like proteins (LRR-RLPs) are ubiquitous cell surface receptors lacking a cytoplasmic signalling domain. For most of these LRR-RLPs, it remained enigmatic how they activate cellular responses upon ligand perception. Recently, the LRR-receptor-like kinase (LRR-RLK) SUPPRESSOR OF BIR1-1 (SOBIR1) was shown to be essential for triggering defence responses by certain LRR-RLPs that act as immune receptors. In addition to SOBIR1, the regulatory LRR-RLK BRI1-ASSOCIATED KINASE-1 (BAK1) is also required for LRR-RLP function. Here, we compare the roles of SOBIR1 and BAK1 as regulatory LRR-RLKs in immunity and development. BAK1 has a general regulatory role in plasma membrane-associated receptor complexes comprising LRR-RLPs and/or LRR-RLKs. By contrast, SOBIR1 appears to be specifically required for the function of receptor complexes containing LRR-RLPs.
Original languageEnglish
Pages (from-to)123-132
JournalTrends in Plant Science
Volume19
Issue number2
DOIs
Publication statusPublished - 2014

Keywords

  • plant innate immunity
  • pattern-recognition receptors
  • ethylene-inducing xylanase
  • arabidopsis-thaliana
  • cladosporium-fulvum
  • defense responses
  • cell-death
  • signaling pathways
  • plasma-membrane
  • protein-kinase

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