Trends in Azole resistance in Aspergillus fumigatus, The Netherlands, 1994–2016

Jochem B. Buil; Eveline Snelders; Laura Bedin Denardi; Willem J.G. Melchers; Paul E. Verweij

doi:10.3201/eid2501.171925

Trends in Azole resistance in Aspergillus fumigatus, The Netherlands, 1994–2016

Jochem B. Buil^*, Eveline Snelders, Laura Bedin Denardi, Willem J.G. Melchers, Paul E. Verweij

^*Corresponding author for this work

Research output: Contribution to journal › Letter › Academic › peer-review

31 Citations (Scopus)

Abstract

We investigated azole resistance in Aspergillus fumigatus in a tertiary reference hospital in the Netherlands during 1994–2016. The 5-year patient-adjusted proportion of resistance increased from 0.79% for 1996–2001 to 4.25% for 2002–2006, 7.17% for 2007–2011, and 7.04% for 2012–2016. However, we observed substantial variation between years.

Original language	English
Pages (from-to)	176-178
Journal	Emerging Infectious Diseases
Volume	25
Issue number	1
DOIs	https://doi.org/10.3201/eid2501.171925
Publication status	Published - 1 Jan 2019

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10.3201/eid2501.171925

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abstract = "We investigated azole resistance in Aspergillus fumigatus in a tertiary reference hospital in the Netherlands during 1994–2016. The 5-year patient-adjusted proportion of resistance increased from 0.79% for 1996–2001 to 4.25% for 2002–2006, 7.17% for 2007–2011, and 7.04% for 2012–2016. However, we observed substantial variation between years.",

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AU - Buil, Jochem B.

AU - Snelders, Eveline

AU - Denardi, Laura Bedin

AU - Melchers, Willem J.G.

AU - Verweij, Paul E.

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N2 - We investigated azole resistance in Aspergillus fumigatus in a tertiary reference hospital in the Netherlands during 1994–2016. The 5-year patient-adjusted proportion of resistance increased from 0.79% for 1996–2001 to 4.25% for 2002–2006, 7.17% for 2007–2011, and 7.04% for 2012–2016. However, we observed substantial variation between years.

AB - We investigated azole resistance in Aspergillus fumigatus in a tertiary reference hospital in the Netherlands during 1994–2016. The 5-year patient-adjusted proportion of resistance increased from 0.79% for 1996–2001 to 4.25% for 2002–2006, 7.17% for 2007–2011, and 7.04% for 2012–2016. However, we observed substantial variation between years.

U2 - 10.3201/eid2501.171925

DO - 10.3201/eid2501.171925

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AN - SCOPUS:85058753015

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SP - 176

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JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

SN - 1080-6040

IS - 1

ER -

Trends in Azole resistance in Aspergillus fumigatus, The Netherlands, 1994–2016

Abstract

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