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We previously reported that cattle were affected by a prion disorder that differed from bovine spongiform encephalopathy (BSE) by showing distinct molecular features of disease-associated protease-resistant prion protein (PrPres). We show that intracerebral injection of such isolates into C57BL/6 mice produces a disease with preservation of PrPres molecular features distinct from BSE.
|Journal||Emerging Infectious Diseases|
|Publication status||Published - 2006|
- spongiform encephalopathy
- molecular analysis