Transmission of new bovine prion to mice

T.G.M. Baron, A.G. Biacabe, A. Bencsik, J.P.M. Langeveld

    Research output: Contribution to journalArticleAcademicpeer-review

    48 Citations (Scopus)

    Abstract

    We previously reported that cattle were affected by a prion disorder that differed from bovine spongiform encephalopathy (BSE) by showing distinct molecular features of disease-associated protease-resistant prion protein (PrPres). We show that intracerebral injection of such isolates into C57BL/6 mice produces a disease with preservation of PrPres molecular features distinct from BSE.
    Original languageEnglish
    Pages (from-to)1125-1128
    JournalEmerging Infectious Diseases
    Volume12
    Issue number7
    Publication statusPublished - 2006

    Keywords

    • creutzfeldt-jakob-disease
    • spongiform encephalopathy
    • molecular analysis
    • scrapie
    • protein
    • agent
    • bse

    Fingerprint Dive into the research topics of 'Transmission of new bovine prion to mice'. Together they form a unique fingerprint.

  • Projects

    TSE's (WOT-01-002-001.01)

    van Keulen, L.

    1/01/0831/12/20

    Project: EZproject

    Cite this

    Baron, T. G. M., Biacabe, A. G., Bencsik, A., & Langeveld, J. P. M. (2006). Transmission of new bovine prion to mice. Emerging Infectious Diseases, 12(7), 1125-1128. https://edepot.wur.nl/32466