Transmission of F4+ E. coli in groups of early weaned piglets

P.L. Geenen, D. Döpfer, J. van der Meulen, M.C.M. de Jong

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Abstract

The aim of this study was to estimate transmission parameters of enterotoxigenic F4+ Escherichia coli F4 (F4+ E. coli) in groups of early weaned piglets with F4-receptor-positive (F4R+) and F4-receptor-negative piglets (F4R[minus sign]). Transmission of F4+ E. coli was quantified in four heterogeneous groups of F4R+ and F4R[minus sign] piglets. Infectiousness was determined by the number of F4+ E. coli/g faeces shed during 8 days. Transmission parameters were estimated using generalized linear models assuming a stochastic SIR model. F4R+ piglets were found to be more susceptible than F4R[minus sign] piglets, but F4R+ and F4R[minus sign] piglets were not different in infectiousness. The reproduction ratios for homogeneous F4R+ and F4R[minus sign] populations were estimated as 6·37 (95% CI 1·89¿21·48) and 0·02 (95% CI 0·00¿1·13) respectively. The implication of these results is that in order to prevent major outbreaks, the fraction of F4R+ piglets should be small (approximately 10% or less). Therefore, selective breeding programmes could contribute to reducing F4+ E. coli-related diarrhoea and transmission.
Original languageEnglish
Pages (from-to)459-468
Number of pages10
JournalEpidemiology and Infection
Volume133
Issue number3
DOIs
Publication statusPublished - 2005

Keywords

  • postweaning diarrhea
  • intestinal receptor
  • brush-borders
  • pigs
  • adhesion
  • k88
  • prevalence
  • phenotypes
  • diseases
  • fimbriae

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