Translating the human microbiome

J. Brown, W.M. de Vos, P.S. Distefano, J. Doré, C. Huttenhower, R. Knight, T.D. Lawley, J. Raes, P. Turnbaugh

Research output: Contribution to journalEditorialAcademicpeer-review

17 Citations (Scopus)

Abstract

Over the past decade, an explosion of descriptive analyses from initiatives, such as the Human Microbiome Project (HMP) and the MetaHIT project, have begun to delineate the human microbiome. Inhabitants of the intestinal tract, nasal passages, oral cavities, skin, gastrointestinal tract and urogenital tract have been identified using whole genome sequencing, cultivation, metagenomics, metatranscriptomics, metaproteomics and metabolomics. Generation of these data has led to an improved understanding of the contribution of the human microbiome to physiology, health and disease. Nature Biotechnology approached several experts to seek their views on what steps need to be taken to move from descriptive microbiome biology to targeted therapies that tackle diseases in which microbiome dysfunction is a contributory factor
LanguageEnglish
Pages304-308
JournalNature Biotechnology
Volume31
Issue number4
DOIs
Publication statusPublished - 2013

Fingerprint

Microbiota
Physiology
Biotechnology
Explosions
Skin
Genes
Health
Metagenomics
Metabolomics
Nose
Mouth
Gastrointestinal Tract
Genome

Cite this

Brown, J., de Vos, W. M., Distefano, P. S., Doré, J., Huttenhower, C., Knight, R., ... Turnbaugh, P. (2013). Translating the human microbiome. Nature Biotechnology, 31(4), 304-308. https://doi.org/10.1038/nbt.2543
Brown, J. ; de Vos, W.M. ; Distefano, P.S. ; Doré, J. ; Huttenhower, C. ; Knight, R. ; Lawley, T.D. ; Raes, J. ; Turnbaugh, P. / Translating the human microbiome. In: Nature Biotechnology. 2013 ; Vol. 31, No. 4. pp. 304-308.
@article{d7f8713d7a5b4a7aa8862d8d754235e1,
title = "Translating the human microbiome",
abstract = "Over the past decade, an explosion of descriptive analyses from initiatives, such as the Human Microbiome Project (HMP) and the MetaHIT project, have begun to delineate the human microbiome. Inhabitants of the intestinal tract, nasal passages, oral cavities, skin, gastrointestinal tract and urogenital tract have been identified using whole genome sequencing, cultivation, metagenomics, metatranscriptomics, metaproteomics and metabolomics. Generation of these data has led to an improved understanding of the contribution of the human microbiome to physiology, health and disease. Nature Biotechnology approached several experts to seek their views on what steps need to be taken to move from descriptive microbiome biology to targeted therapies that tackle diseases in which microbiome dysfunction is a contributory factor",
author = "J. Brown and {de Vos}, W.M. and P.S. Distefano and J. Dor{\'e} and C. Huttenhower and R. Knight and T.D. Lawley and J. Raes and P. Turnbaugh",
year = "2013",
doi = "10.1038/nbt.2543",
language = "English",
volume = "31",
pages = "304--308",
journal = "Nature Biotechnology",
issn = "1087-0156",
publisher = "Nature Publishing Group",
number = "4",

}

Brown, J, de Vos, WM, Distefano, PS, Doré, J, Huttenhower, C, Knight, R, Lawley, TD, Raes, J & Turnbaugh, P 2013, 'Translating the human microbiome', Nature Biotechnology, vol. 31, no. 4, pp. 304-308. https://doi.org/10.1038/nbt.2543

Translating the human microbiome. / Brown, J.; de Vos, W.M.; Distefano, P.S.; Doré, J.; Huttenhower, C.; Knight, R.; Lawley, T.D.; Raes, J.; Turnbaugh, P.

In: Nature Biotechnology, Vol. 31, No. 4, 2013, p. 304-308.

Research output: Contribution to journalEditorialAcademicpeer-review

TY - JOUR

T1 - Translating the human microbiome

AU - Brown, J.

AU - de Vos, W.M.

AU - Distefano, P.S.

AU - Doré, J.

AU - Huttenhower, C.

AU - Knight, R.

AU - Lawley, T.D.

AU - Raes, J.

AU - Turnbaugh, P.

PY - 2013

Y1 - 2013

N2 - Over the past decade, an explosion of descriptive analyses from initiatives, such as the Human Microbiome Project (HMP) and the MetaHIT project, have begun to delineate the human microbiome. Inhabitants of the intestinal tract, nasal passages, oral cavities, skin, gastrointestinal tract and urogenital tract have been identified using whole genome sequencing, cultivation, metagenomics, metatranscriptomics, metaproteomics and metabolomics. Generation of these data has led to an improved understanding of the contribution of the human microbiome to physiology, health and disease. Nature Biotechnology approached several experts to seek their views on what steps need to be taken to move from descriptive microbiome biology to targeted therapies that tackle diseases in which microbiome dysfunction is a contributory factor

AB - Over the past decade, an explosion of descriptive analyses from initiatives, such as the Human Microbiome Project (HMP) and the MetaHIT project, have begun to delineate the human microbiome. Inhabitants of the intestinal tract, nasal passages, oral cavities, skin, gastrointestinal tract and urogenital tract have been identified using whole genome sequencing, cultivation, metagenomics, metatranscriptomics, metaproteomics and metabolomics. Generation of these data has led to an improved understanding of the contribution of the human microbiome to physiology, health and disease. Nature Biotechnology approached several experts to seek their views on what steps need to be taken to move from descriptive microbiome biology to targeted therapies that tackle diseases in which microbiome dysfunction is a contributory factor

U2 - 10.1038/nbt.2543

DO - 10.1038/nbt.2543

M3 - Editorial

VL - 31

SP - 304

EP - 308

JO - Nature Biotechnology

T2 - Nature Biotechnology

JF - Nature Biotechnology

SN - 1087-0156

IS - 4

ER -

Brown J, de Vos WM, Distefano PS, Doré J, Huttenhower C, Knight R et al. Translating the human microbiome. Nature Biotechnology. 2013;31(4):304-308. https://doi.org/10.1038/nbt.2543