Transcriptomic and epigenomic network analysis reveals chicken physiological reactions against heat stress

Marinus F.W. te Pas; Woncheoul Park; Krishnamoorthy Srikanth; Himansu Kumar; Steve Kemp; Jun Mo Kim; Dajeong Lim; Ole Madsen; Henry van den Brand; Jong Eun Park

doi:10.1016/B978-0-323-91810-7.00002-9

Transcriptomic and epigenomic network analysis reveals chicken physiological reactions against heat stress

Marinus F.W. te Pas, Woncheoul Park, Krishnamoorthy Srikanth, Himansu Kumar, Steve Kemp, Jun Mo Kim, Dajeong Lim, Ole Madsen, Henry van den Brand, Jong Eun Park

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

2 Citations (Scopus)

Abstract

Global warming is expected to result in larger temperature fluctuations by which heat stress may become an important stressor for animals, affecting health and productivity. Animals can cope with and adapt to heat stress by changing their physiology. To investigate general physiological reactions to heat stress in muscle and heart tissues of chickens we combined results from three independent experiments. Two experiments studied the transcriptome profiles of heart and muscle tissues of mature chickens using heat stress adapted and nonadapted chickens. One experiment studied the epigenome changes of heat stress during chicken egg incubation. In all three datasets epigenome changes were important biological response mechanisms, which may underlie genome-wide regulation of the affected biological mechanisms. Pre and postnatal heat stress reaction showed changed expression of genes related to metabolic rate, energy, and protein metabolism. Furthermore, tissue integrity may be affected due to changed cell−cell contacts, vascularization, and growth reduction.

Original language	English
Title of host publication	Transcriptome Profiling
Subtitle of host publication	Progress and Prospects
Publisher	Elsevier
Chapter	12
Pages	333-359
Number of pages	27
ISBN (Electronic)	9780323918107
ISBN (Print)	9780323972314
DOIs	https://doi.org/10.1016/B978-0-323-91810-7.00002-9
Publication status	Published - 7 Oct 2022

Keywords

Chicken
datasets with different experimental designs
gene networks
heat stress
pathways
transcriptome and epigenome comparisons

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10.1016/B978-0-323-91810-7.00002-9

https://edepot.wur.nl/583976Licence: Taverne

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te Pas, M. F. W., Park, W., Srikanth, K., Kumar, H., Kemp, S., Kim, J. M., Lim, D., Madsen, O., van den Brand, H., & Park, J. E. (2022). Transcriptomic and epigenomic network analysis reveals chicken physiological reactions against heat stress. In Transcriptome Profiling: Progress and Prospects (pp. 333-359). Elsevier. https://doi.org/10.1016/B978-0-323-91810-7.00002-9

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title = "Transcriptomic and epigenomic network analysis reveals chicken physiological reactions against heat stress",

abstract = "Global warming is expected to result in larger temperature fluctuations by which heat stress may become an important stressor for animals, affecting health and productivity. Animals can cope with and adapt to heat stress by changing their physiology. To investigate general physiological reactions to heat stress in muscle and heart tissues of chickens we combined results from three independent experiments. Two experiments studied the transcriptome profiles of heart and muscle tissues of mature chickens using heat stress adapted and nonadapted chickens. One experiment studied the epigenome changes of heat stress during chicken egg incubation. In all three datasets epigenome changes were important biological response mechanisms, which may underlie genome-wide regulation of the affected biological mechanisms. Pre and postnatal heat stress reaction showed changed expression of genes related to metabolic rate, energy, and protein metabolism. Furthermore, tissue integrity may be affected due to changed cell−cell contacts, vascularization, and growth reduction.",

keywords = "Chicken, datasets with different experimental designs, gene networks, heat stress, pathways, transcriptome and epigenome comparisons",

author = "{te Pas}, {Marinus F.W.} and Woncheoul Park and Krishnamoorthy Srikanth and Himansu Kumar and Steve Kemp and Kim, {Jun Mo} and Dajeong Lim and Ole Madsen and {van den Brand}, Henry and Park, {Jong Eun}",

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doi = "10.1016/B978-0-323-91810-7.00002-9",

language = "English",

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T1 - Transcriptomic and epigenomic network analysis reveals chicken physiological reactions against heat stress

AU - te Pas, Marinus F.W.

AU - Park, Woncheoul

AU - Srikanth, Krishnamoorthy

AU - Kumar, Himansu

AU - Kemp, Steve

AU - Kim, Jun Mo

AU - Lim, Dajeong

AU - Madsen, Ole

AU - van den Brand, Henry

AU - Park, Jong Eun

PY - 2022/10/7

Y1 - 2022/10/7

N2 - Global warming is expected to result in larger temperature fluctuations by which heat stress may become an important stressor for animals, affecting health and productivity. Animals can cope with and adapt to heat stress by changing their physiology. To investigate general physiological reactions to heat stress in muscle and heart tissues of chickens we combined results from three independent experiments. Two experiments studied the transcriptome profiles of heart and muscle tissues of mature chickens using heat stress adapted and nonadapted chickens. One experiment studied the epigenome changes of heat stress during chicken egg incubation. In all three datasets epigenome changes were important biological response mechanisms, which may underlie genome-wide regulation of the affected biological mechanisms. Pre and postnatal heat stress reaction showed changed expression of genes related to metabolic rate, energy, and protein metabolism. Furthermore, tissue integrity may be affected due to changed cell−cell contacts, vascularization, and growth reduction.

AB - Global warming is expected to result in larger temperature fluctuations by which heat stress may become an important stressor for animals, affecting health and productivity. Animals can cope with and adapt to heat stress by changing their physiology. To investigate general physiological reactions to heat stress in muscle and heart tissues of chickens we combined results from three independent experiments. Two experiments studied the transcriptome profiles of heart and muscle tissues of mature chickens using heat stress adapted and nonadapted chickens. One experiment studied the epigenome changes of heat stress during chicken egg incubation. In all three datasets epigenome changes were important biological response mechanisms, which may underlie genome-wide regulation of the affected biological mechanisms. Pre and postnatal heat stress reaction showed changed expression of genes related to metabolic rate, energy, and protein metabolism. Furthermore, tissue integrity may be affected due to changed cell−cell contacts, vascularization, and growth reduction.

KW - Chicken

KW - datasets with different experimental designs

KW - gene networks

KW - heat stress

KW - pathways

KW - transcriptome and epigenome comparisons

U2 - 10.1016/B978-0-323-91810-7.00002-9

DO - 10.1016/B978-0-323-91810-7.00002-9

M3 - Chapter

AN - SCOPUS:85142838461

SN - 9780323972314

SP - 333

EP - 359

BT - Transcriptome Profiling

PB - Elsevier

ER -

Transcriptomic and epigenomic network analysis reveals chicken physiological reactions against heat stress

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Keywords

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