Trace analysis of polychlorinated dibenzo-p-dioxins, dibenzofurnas and WHO polychlorinated biphenyls in food using comprehensive two-dimensional gas chromatography with elctron-capture detection

C. Danielsson, K. Wiberg, P. Korytar, S. Bergek, U.A.Th. Brinkman, P. Haglund

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    Abstract

    Trace analysis of 2,3,7,8-polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and the 12 WHO-PCBs (four non-ortho and eight mono-ortho congeners that have been assigned toxic equivalence factors, TEFs, by the World Health Organisation) was conducted by comprehensive two-dimensional gas chromatography with a micro electron-capture detector (GC × GC-¿ECD). Four food matrices (fish oil from herring, spiked cows¿ milk, vegetable oil and an eel extract) were analysed by two GC × GC laboratories, and four GC¿HRMS laboratories generated reference values. The two GC × GC laboratories used different column combinations for separating the target analytes. For the first dimension, non-polar DB-XLB and VF-1 columns were used, and for the second dimension, an LC-50 liquid crystalline column with unique selectivity for planar compounds. The congener-specific and total toxic equivalence (TEQ) data obtained using DB-XLB × LC-50 were in good agreement with results obtained by the GC¿HRMS laboratories. The WHO-PCB data obtained with the VF-1 × LC-50 combination was also good, but the PCDD/F concentrations were sometimes overestimated due to matrix interferences. GC × GC-¿ECD using DB-XLB × LC-50 seems to fulfil the European Community requirements of a screening method for PCDD/F and WHO-PCB TEQ in food
    Original languageEnglish
    Pages (from-to)61-70
    JournalJournal of Chromatography. A, Including electrophoresis and other separation methods
    Volume1086
    Issue number1-2
    DOIs
    Publication statusPublished - 2005

    Keywords

    • mono-ortho
    • pcbs
    • interface
    • samples
    • carbon
    • column
    • pcdfs
    • pcdds

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