Abstract
Abstract
Two advanced techniques have been compared to enhance bioprocess monitoring and
control by online reconstruction of biomass and specific growth rate for feedback
control: a software sensor based on standard measurements of the oxygen uptake rate
and inline near infrared spectroscopy. An automatic search method for wavelength
selection was proposed to enhance the prection ability of the near infrared method.
Both techniques perform well, however when it comes to feedback control, the software
sensor is preferred, because it is more robust against variations in the operating
conditions and noise. The results are shown on real cultivations of Bordetella pertussis.
Original language | English |
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Publication status | Published - 2009 |
Event | CHEMPOR 2008 - Duration: 4 Sept 2008 → 6 Sept 2008 |
Conference/symposium
Conference/symposium | CHEMPOR 2008 |
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Period | 4/09/08 → 6/09/08 |