Total synthesis and bioactivity of some naturally occurring pterulones

B.W.T. Gruijters; A. van Veldhuizen; C.A.G.M. Weijers; J.B.P.A. Wijnberg

doi:10.1021/np010510m

Total synthesis and bioactivity of some naturally occurring pterulones

B.W.T. Gruijters, A. van Veldhuizen, C.A.G.M. Weijers, J.B.P.A. Wijnberg

Research output: Contribution to journal › Article › Academic › peer-review

22 Citations (Scopus)

Abstract

The naturally occurring pterulones 1, 3, and 13 were synthesized in high overall yield from readily available methyl 3-(2-propenyl)-4-(2-propenyloxy)benzoate (6) by employing ring-closing metathesis (RCM) as a key step. The biological activities of the synthesized pterulones were tested using cells of Rhodotorula glutinis and Saccharomyces cerevisiae.

Original language	English
Pages (from-to)	558-561
Journal	Journal of Natural Products
Volume	65
Issue number	4
DOIs	https://doi.org/10.1021/np010510m
Publication status	Published - 2002

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title = "Total synthesis and bioactivity of some naturally occurring pterulones",

abstract = "The naturally occurring pterulones 1, 3, and 13 were synthesized in high overall yield from readily available methyl 3-(2-propenyl)-4-(2-propenyloxy)benzoate (6) by employing ring-closing metathesis (RCM) as a key step. The biological activities of the synthesized pterulones were tested using cells of Rhodotorula glutinis and Saccharomyces cerevisiae.",

author = "B.W.T. Gruijters and {van Veldhuizen}, A. and C.A.G.M. Weijers and J.B.P.A. Wijnberg",

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AU - Gruijters, B.W.T.

AU - van Veldhuizen, A.

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AU - Wijnberg, J.B.P.A.

PY - 2002

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AB - The naturally occurring pterulones 1, 3, and 13 were synthesized in high overall yield from readily available methyl 3-(2-propenyl)-4-(2-propenyloxy)benzoate (6) by employing ring-closing metathesis (RCM) as a key step. The biological activities of the synthesized pterulones were tested using cells of Rhodotorula glutinis and Saccharomyces cerevisiae.

U2 - 10.1021/np010510m

DO - 10.1021/np010510m

M3 - Article

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VL - 65

SP - 558

EP - 561

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 4

ER -

Total synthesis and bioactivity of some naturally occurring pterulones

Abstract

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