Thermally sensitive dual fluorescent polymeric micelles for probing cell properties

F. Li Feng, A.H. Westphal, A.T.M. Marcelis, E.J.R. Sudhölter, M.A. Cohen Stuart, F.A.M. Leermakers

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Abstract

Dual fluorescent micelles with a hydrophobic probe (HMA) embedded in the micelle core and a hydrophilic probe (TRITC) attached on the micelle corona were prepared. These micelles can act as nanometre-sized thermal sensors. Within a short temperature range, the fluorescent emission of the micelles changes strongly and reversibly as a function of temperature. These micelles can be easily taken up by human HeLa cells and can potentially be used as intracellular thermometers.
Original languageEnglish
Pages (from-to)11211-11215
JournalSoft Matter
Volume7
Issue number7
DOIs
Publication statusPublished - 2011

Keywords

  • block-copolymers
  • stabilization
  • complexes
  • vesicles

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