The value of conserved samples in gene banks for animal breeding in the MRIJ cattle breed

Research output: Chapter in Book/Report/Conference proceedingConference paper

Abstract

Population size of the Meuse-Rhine-Yssel cattle breed has decreased considerably between 1992 and 2014, while total genetic merit increased as a result of an effective breeding program. Genetic diversity decreased at the same time and inbreeding rate was 1.24% per generation. In addition to the genetic diversity in the live population, semen samples have been conserved in gene bank collections. We characterized genetic diversity in conserved samples and the current bull population by typing DNA with the 50K SNP chip, and investigated whether using conserved samples may help to restore genetic diversity in the breeding program, as measured by expected heterozygosity (Hexp), and what the effect is on total genetic merit. Hexp is 0.334 in the conserved bulls and 0.324 in the current breeding bulls. Hexp in the next generation can be maximised to 0.333 when using only current bulls, but to 0.344 when including conserved bulls. When the Hexp is constrained to 0.322 genetic merit can be maximised to 101 using current bulls only and to 105 when including conserved bulls. Under a more strict constraint of 0.331 genetic merit can increase to 56 for current and to 72 including conserved bulls. Conserved samples from gene bank collections may thus help to restore genetic diversity and even increase genetic merit when loss of diversity is constrained.
Original languageEnglish
Title of host publicationProceedings of the World Congress on Genetics Applied to Livestock Production
Subtitle of host publicationVolume Challenges - Species Conservation
PublisherWCGALP
Number of pages5
Publication statusPublished - 2018
Event11th World Congress on Genetics Applied to Livestock Production - Auckland, New Zealand
Duration: 11 Feb 201816 Feb 2018

Conference

Conference11th World Congress on Genetics Applied to Livestock Production
CountryNew Zealand
CityAuckland
Period11/02/1816/02/18

Fingerprint

gene banks
animal breeding
cattle breeds
bulls
genetic merit
genetic variation
sampling
breeding
DNA fingerprinting
inbreeding
semen
heterozygosity
population size

Cite this

Eynard, S. E., Calus, M. P. L., Hulsegge, I., Hiemstra, S. J., & Windig, J. J. (2018). The value of conserved samples in gene banks for animal breeding in the MRIJ cattle breed. In Proceedings of the World Congress on Genetics Applied to Livestock Production: Volume Challenges - Species Conservation [191] WCGALP.
Eynard, S.E. ; Calus, M.P.L. ; Hulsegge, Ina ; Hiemstra, S.J. ; Windig, J.J. / The value of conserved samples in gene banks for animal breeding in the MRIJ cattle breed. Proceedings of the World Congress on Genetics Applied to Livestock Production: Volume Challenges - Species Conservation. WCGALP, 2018.
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abstract = "Population size of the Meuse-Rhine-Yssel cattle breed has decreased considerably between 1992 and 2014, while total genetic merit increased as a result of an effective breeding program. Genetic diversity decreased at the same time and inbreeding rate was 1.24{\%} per generation. In addition to the genetic diversity in the live population, semen samples have been conserved in gene bank collections. We characterized genetic diversity in conserved samples and the current bull population by typing DNA with the 50K SNP chip, and investigated whether using conserved samples may help to restore genetic diversity in the breeding program, as measured by expected heterozygosity (Hexp), and what the effect is on total genetic merit. Hexp is 0.334 in the conserved bulls and 0.324 in the current breeding bulls. Hexp in the next generation can be maximised to 0.333 when using only current bulls, but to 0.344 when including conserved bulls. When the Hexp is constrained to 0.322 genetic merit can be maximised to 101 using current bulls only and to 105 when including conserved bulls. Under a more strict constraint of 0.331 genetic merit can increase to 56 for current and to 72 including conserved bulls. Conserved samples from gene bank collections may thus help to restore genetic diversity and even increase genetic merit when loss of diversity is constrained.",
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Eynard, SE, Calus, MPL, Hulsegge, I, Hiemstra, SJ & Windig, JJ 2018, The value of conserved samples in gene banks for animal breeding in the MRIJ cattle breed. in Proceedings of the World Congress on Genetics Applied to Livestock Production: Volume Challenges - Species Conservation., 191, WCGALP, 11th World Congress on Genetics Applied to Livestock Production, Auckland, New Zealand, 11/02/18.

The value of conserved samples in gene banks for animal breeding in the MRIJ cattle breed. / Eynard, S.E.; Calus, M.P.L.; Hulsegge, Ina; Hiemstra, S.J.; Windig, J.J.

Proceedings of the World Congress on Genetics Applied to Livestock Production: Volume Challenges - Species Conservation. WCGALP, 2018. 191.

Research output: Chapter in Book/Report/Conference proceedingConference paper

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Eynard SE, Calus MPL, Hulsegge I, Hiemstra SJ, Windig JJ. The value of conserved samples in gene banks for animal breeding in the MRIJ cattle breed. In Proceedings of the World Congress on Genetics Applied to Livestock Production: Volume Challenges - Species Conservation. WCGALP. 2018. 191