The use of mushroom-forming fungi for the production of N-glycosylated therapeutic proteins

E. Berends; K. Scholtmeijer; H.A.B. Wösten; H.J. Bosch; L.G. Lugones

doi:10.1016/j.tim.2009.07.002

The use of mushroom-forming fungi for the production of N-glycosylated therapeutic proteins

E. Berends, K. Scholtmeijer, H.A.B. Wösten, H.J. Bosch, L.G. Lugones

Research output: Contribution to journal › Article › Academic › peer-review

21 Citations (Scopus)

Abstract

The market for N-glycosylated therapeutic proteins represents multi-billion dollars in sales and is growing more than 10% each year. This requires cost-effective production platforms that display correct and homogeneous N-glycosylation. Based on recent results, we propose to use mushroom-forming basidiomycetes for the production of N-glycosylated therapeutic proteins

Original language	English
Pages (from-to)	439-443
Journal	Trends in Microbiology
Volume	17
Issue number	10
DOIs	https://doi.org/10.1016/j.tim.2009.07.002
Publication status	Published - 2009

Keywords

basidiomycete schizophyllum-commune
filamentous fungi
pichia-pastoris
oligosaccharides
laccase
glycans
scale
roles
yeast

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tim.2009.07.002

Cite this

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abstract = "The market for N-glycosylated therapeutic proteins represents multi-billion dollars in sales and is growing more than 10\% each year. This requires cost-effective production platforms that display correct and homogeneous N-glycosylation. Based on recent results, we propose to use mushroom-forming basidiomycetes for the production of N-glycosylated therapeutic proteins",

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AU - Bosch, H.J.

AU - Lugones, L.G.

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KW - basidiomycete schizophyllum-commune

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KW - pichia-pastoris

KW - oligosaccharides

KW - laccase

KW - glycans

KW - scale

KW - roles

KW - yeast

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DO - 10.1016/j.tim.2009.07.002

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ER -

The use of mushroom-forming fungi for the production of N-glycosylated therapeutic proteins

Abstract

Keywords

UN SDGs

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