The transmission characteristics of A/Chicken/Pennsylvania/83 influenza virus, an experimental approach

J.A. van der Goot; G. Koch; M.C.M. de Jong; R.M. van Boven

doi:10.1637/0005-2086-47.s3.939

The transmission characteristics of A/Chicken/Pennsylvania/83 influenza virus, an experimental approach

J.A. van der Goot
, G. Koch
, M.C.M. de Jong
, R.M. van Boven

Research output: Contribution to journal › Article › Academic › peer-review

30 Citations (Scopus)

Abstract

High-pathogenicity avian influenza (HPAI) viruses emerged from low-pathogenicity avian influenza (LPAI) viruses in Pennsylvania (1983-84), Mexico (1994-95), and Italy (1999-2000). Here we focus on the question of why the HPAI virus supersedes the LPAI virus, once it has appeared during the epidemic. To study this, we used an experimental model in chickens that enabled us to estimate the reproduction ratio (R-0). Using this model, we determined the R-0 of the A/Chicken/Pennsylvania/21525/83 (LPAI) and of the A/Chicken/ Pennsylvania/ 1370/83 (HPAI). Comparing the R-0 of both viruses, we concluded that the R-0 of the HPAI virus is significantly higher than the R-0 of the LPAI.

Original language	English
Pages (from-to)	939-941
Journal	Avian Diseases
Volume	47
Issue number	s3
DOIs	https://doi.org/10.1637/0005-2086-47.s3.939
Publication status	Published - 2003

Keywords

Avian influenza
Chicken
Final size
Transmission

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10.1637/0005-2086-47.s3.939

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title = "The transmission characteristics of A/Chicken/Pennsylvania/83 influenza virus, an experimental approach",

abstract = "High-pathogenicity avian influenza (HPAI) viruses emerged from low-pathogenicity avian influenza (LPAI) viruses in Pennsylvania (1983-84), Mexico (1994-95), and Italy (1999-2000). Here we focus on the question of why the HPAI virus supersedes the LPAI virus, once it has appeared during the epidemic. To study this, we used an experimental model in chickens that enabled us to estimate the reproduction ratio (R-0). Using this model, we determined the R-0 of the A/Chicken/Pennsylvania/21525/83 (LPAI) and of the A/Chicken/ Pennsylvania/ 1370/83 (HPAI). Comparing the R-0 of both viruses, we concluded that the R-0 of the HPAI virus is significantly higher than the R-0 of the LPAI.",

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T1 - The transmission characteristics of A/Chicken/Pennsylvania/83 influenza virus, an experimental approach

AU - van der Goot, J.A.

AU - Koch, G.

AU - de Jong, M.C.M.

AU - van Boven, R.M.

PY - 2003

Y1 - 2003

N2 - High-pathogenicity avian influenza (HPAI) viruses emerged from low-pathogenicity avian influenza (LPAI) viruses in Pennsylvania (1983-84), Mexico (1994-95), and Italy (1999-2000). Here we focus on the question of why the HPAI virus supersedes the LPAI virus, once it has appeared during the epidemic. To study this, we used an experimental model in chickens that enabled us to estimate the reproduction ratio (R-0). Using this model, we determined the R-0 of the A/Chicken/Pennsylvania/21525/83 (LPAI) and of the A/Chicken/ Pennsylvania/ 1370/83 (HPAI). Comparing the R-0 of both viruses, we concluded that the R-0 of the HPAI virus is significantly higher than the R-0 of the LPAI.

AB - High-pathogenicity avian influenza (HPAI) viruses emerged from low-pathogenicity avian influenza (LPAI) viruses in Pennsylvania (1983-84), Mexico (1994-95), and Italy (1999-2000). Here we focus on the question of why the HPAI virus supersedes the LPAI virus, once it has appeared during the epidemic. To study this, we used an experimental model in chickens that enabled us to estimate the reproduction ratio (R-0). Using this model, we determined the R-0 of the A/Chicken/Pennsylvania/21525/83 (LPAI) and of the A/Chicken/ Pennsylvania/ 1370/83 (HPAI). Comparing the R-0 of both viruses, we concluded that the R-0 of the HPAI virus is significantly higher than the R-0 of the LPAI.

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KW - Final size

KW - Transmission

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DO - 10.1637/0005-2086-47.s3.939

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JO - Avian Diseases

JF - Avian Diseases

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The transmission characteristics of A/Chicken/Pennsylvania/83 influenza virus, an experimental approach

Abstract

Keywords

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