The relationship between microsomal enzyme induction and liver tumour formation : a study on the effects of xenobiotic and naturally occurring microsomal enzyme inducers on livers of male CF-1 mice

Agriculture & Biology

• animals 7%
• artificial diets 9%
• dieldrin 94%
• diet 12%
• drugs 5%
• enzymes 33%
• epoxides 15%
• gene induction 85%
• glutathione 7%
• hepatocytes 7%
• hyperplasia 18%
• incidence 17%
• lesions (animal) 6%
• liver 44%
• liver neoplasms 100%
• lungs 6%
• metabolism 4%
• metastasis 10%
• mice 43%
• neoplasms 12%
• oxygenases 8%
• rodents 7%
• sawdust 28%
• transferases 16%
• unspecific monooxygenase 11%
• xenobiotics 79%