The relationship between microsomal enzyme induction and liver tumour formation : a study on the effects of xenobiotic and naturally occurring microsomal enzyme inducers on livers of male CF-1 mice

Agriculture & Biology

• liver neoplasms 100%
• dieldrin 94%
• gene induction 85%
• xenobiotics 79%
• liver 44%
• mice 43%
• enzymes 33%
• sawdust 28%
• hyperplasia 18%
• incidence 17%
• transferases 16%
• epoxides 15%
• diet 12%
• neoplasms 12%
• unspecific monooxygenase 11%
• metastasis 10%
• artificial diets 9%
• oxygenases 8%
• hepatocytes 7%
• glutathione 7%
• animals 7%
• rodents 7%
• lesions (animal) 6%
• lungs 6%
• drugs 5%
• metabolism 4%