TY - JOUR
T1 - The PREVIEW-Population studies: design and methods
AU - Feskens, E.J.M.
AU - Sluik, D.
AU - Fogelholm, M.
AU - Brand-Miller, J.
AU - Poppit, S.
AU - Tremblay, A.
AU - Raben, A.
PY - 2013
Y1 - 2013
N2 - The overall objective of PREVIEW population studies is to
substantiate the findings in the intervention study with data
from five longitudinal population studies from Europe, New
Zealand and Canada, covering the entire lifespan. It will be
evaluated whether protein intake, glycaemic index (GI), and
physical activity, are predictive of diabetes and its cardiovascular
consequences. This will add insight into the natural history
of diabetes, by considering specific dietary and exercise factors.
The following epidemiological studies will be analysed:
1. The Netherlands: LifeLines (2006-ongoing), a three-generation
population-based study in 165,000 people 4-90+y and
NQplus (2011-ongoing), a survey in n=1,750 people 20-70y,
repeated 3 times.
2. Finland: Cardiovascular Risk in Young Finns Study
(1980-2012), a survey in n=3,596 people 3-18y at baseline, repeated
8 times.
3. New Zealand: NZ Adult Nutrition Survey (2008/09), a
cross-sectional survey in n=4,721 people> 15y.
4. Canada: Quebec Family Study (1978-2002), a 3-phase
longitudinal study from ~500 families including ~200 families
with one obese member. A common database of these five population
studies will be generated. Main exposure variables will
be dietary components and physical activity. The outcome will
be diabetes prevalence or incidence, and blood glucose parameters.
Data-analysis will be conducted with meta-analytical
techniques, using a random-effects model to consider heterogeneity
among cohorts. Population attributable risks will give
an estimate on how much of diabetes risk could theoretically
be prevented by modifying these factors. Additionally, given
that GI, one of the key exposures, is not routinely available in
all food tables, a dedicated questionnaire focusing on assessing
GI will be developed. It will be applied to the NQPlus cohort
to gain insight into the quality of the GI results. The research
described here receives funding from the EU Seventh Framework
Programme (FP7/2007-2013) under grant agreement
no. 312057.
AB - The overall objective of PREVIEW population studies is to
substantiate the findings in the intervention study with data
from five longitudinal population studies from Europe, New
Zealand and Canada, covering the entire lifespan. It will be
evaluated whether protein intake, glycaemic index (GI), and
physical activity, are predictive of diabetes and its cardiovascular
consequences. This will add insight into the natural history
of diabetes, by considering specific dietary and exercise factors.
The following epidemiological studies will be analysed:
1. The Netherlands: LifeLines (2006-ongoing), a three-generation
population-based study in 165,000 people 4-90+y and
NQplus (2011-ongoing), a survey in n=1,750 people 20-70y,
repeated 3 times.
2. Finland: Cardiovascular Risk in Young Finns Study
(1980-2012), a survey in n=3,596 people 3-18y at baseline, repeated
8 times.
3. New Zealand: NZ Adult Nutrition Survey (2008/09), a
cross-sectional survey in n=4,721 people> 15y.
4. Canada: Quebec Family Study (1978-2002), a 3-phase
longitudinal study from ~500 families including ~200 families
with one obese member. A common database of these five population
studies will be generated. Main exposure variables will
be dietary components and physical activity. The outcome will
be diabetes prevalence or incidence, and blood glucose parameters.
Data-analysis will be conducted with meta-analytical
techniques, using a random-effects model to consider heterogeneity
among cohorts. Population attributable risks will give
an estimate on how much of diabetes risk could theoretically
be prevented by modifying these factors. Additionally, given
that GI, one of the key exposures, is not routinely available in
all food tables, a dedicated questionnaire focusing on assessing
GI will be developed. It will be applied to the NQPlus cohort
to gain insight into the quality of the GI results. The research
described here receives funding from the EU Seventh Framework
Programme (FP7/2007-2013) under grant agreement
no. 312057.
M3 - Abstract
SN - 0250-6807
VL - 63
SP - 97
EP - 98
JO - Annals of Nutrition & Metabolism
JF - Annals of Nutrition & Metabolism
IS - Suppl.1
ER -
