The molecular basis of co-evolution between Cladosporium fulvum and tomato

P.J.G.M. de Wit; B.F. Brandwagt; H.A. van den Burg; X. Cai; R.A.L. van der Hoorn; C.F. de Jong; J. van 't Klooster; M.J.D. de Kock; M. Kruijt; W.H. Lindhout; R. Luderer; F.L.W. Takken; N. Westerink; J.J.M. Vervoort; M.H.A.J. Joosten

doi:10.1023/A:1020553120889

The molecular basis of co-evolution between Cladosporium fulvum and tomato

P.J.G.M. de Wit, B.F. Brandwagt, H.A. van den Burg, X. Cai, R.A.L. van der Hoorn, C.F. de Jong, J. van 't Klooster, M.J.D. de Kock, M. Kruijt, W.H. Lindhout, R. Luderer, F.L.W. Takken, N. Westerink, J.J.M. Vervoort, M.H.A.J. Joosten

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21 Citations (Scopus)

Abstract

Cladosporium fulvum is a semi-biotrophic pathogen, which causes leaf mold of tomato (Lycopersicon spp.). In our laboratory this pathosystem serves as a model to study gene-for-gene interactions between plants and pathogenic fungi (Joosten & De Wit 1999). Many avirulence (Avr) genes and matching resistance (Cf) genes have been cloned and we are now beginning to understand how their products can induce an array of plant defense responses, including the classic hypersensitive response (HR). Here, we will discuss the latest results of our molecular studies on this interaction. These include the isolation of: (i) two new Avr genes, Avr2 and Avr4E, (ii) the determination of the specificity determinants within the Cf-4 and Cf-9 genes by artificial domain swaps and introduction of point mutations, (iii) the analysis of polymorphism occurring in AVR9-responsive Cf genes occurring in natural populations of L. pimpinellifolium, and finally (iv) the description of an efficient method to identify early HR-related genes.

Original language	English
Pages (from-to)	409-412
Journal	Antonie van Leeuwenhoek: Nederlandsch tijdschrift voor hygiëne, microbiologie en serologie
Volume	81
Issue number	1-4
DOIs	https://doi.org/10.1023/A:1020553120889
Publication status	Published - 2002

Keywords

cladosporium
plant pathogens
solanum
genetic resistance
hypersensitivity

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de Wit, P. J. G. M., Brandwagt, B. F., van den Burg, H. A., Cai, X., van der Hoorn, R. A. L., de Jong, C. F., van 't Klooster, J., de Kock, M. J. D., Kruijt, M., Lindhout, W. H., Luderer, R., Takken, F. L. W., Westerink, N., Vervoort, J. J. M., & Joosten, M. H. A. J. (2002). The molecular basis of co-evolution between Cladosporium fulvum and tomato. Antonie van Leeuwenhoek: Nederlandsch tijdschrift voor hygiëne, microbiologie en serologie, 81(1-4), 409-412. https://doi.org/10.1023/A:1020553120889

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title = "The molecular basis of co-evolution between Cladosporium fulvum and tomato",

abstract = "Cladosporium fulvum is a semi-biotrophic pathogen, which causes leaf mold of tomato (Lycopersicon spp.). In our laboratory this pathosystem serves as a model to study gene-for-gene interactions between plants and pathogenic fungi (Joosten & De Wit 1999). Many avirulence (Avr) genes and matching resistance (Cf) genes have been cloned and we are now beginning to understand how their products can induce an array of plant defense responses, including the classic hypersensitive response (HR). Here, we will discuss the latest results of our molecular studies on this interaction. These include the isolation of: (i) two new Avr genes, Avr2 and Avr4E, (ii) the determination of the specificity determinants within the Cf-4 and Cf-9 genes by artificial domain swaps and introduction of point mutations, (iii) the analysis of polymorphism occurring in AVR9-responsive Cf genes occurring in natural populations of L. pimpinellifolium, and finally (iv) the description of an efficient method to identify early HR-related genes.",

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author = "{de Wit}, P.J.G.M. and B.F. Brandwagt and {van den Burg}, H.A. and X. Cai and {van der Hoorn}, R.A.L. and {de Jong}, C.F. and {van 't Klooster}, J. and {de Kock}, M.J.D. and M. Kruijt and W.H. Lindhout and R. Luderer and F.L.W. Takken and N. Westerink and J.J.M. Vervoort and M.H.A.J. Joosten",

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de Wit, PJGM, Brandwagt, BF, van den Burg, HA, Cai, X, van der Hoorn, RAL, de Jong, CF, van 't Klooster, J, de Kock, MJD, Kruijt, M, Lindhout, WH, Luderer, R, Takken, FLW, Westerink, N, Vervoort, JJM & Joosten, MHAJ 2002, 'The molecular basis of co-evolution between Cladosporium fulvum and tomato', Antonie van Leeuwenhoek: Nederlandsch tijdschrift voor hygiëne, microbiologie en serologie, vol. 81, no. 1-4, pp. 409-412. https://doi.org/10.1023/A:1020553120889

TY - JOUR

T1 - The molecular basis of co-evolution between Cladosporium fulvum and tomato

AU - de Wit, P.J.G.M.

AU - Brandwagt, B.F.

AU - van den Burg, H.A.

AU - Cai, X.

AU - van der Hoorn, R.A.L.

AU - de Jong, C.F.

AU - van 't Klooster, J.

AU - de Kock, M.J.D.

AU - Kruijt, M.

AU - Lindhout, W.H.

AU - Luderer, R.

AU - Takken, F.L.W.

AU - Westerink, N.

AU - Vervoort, J.J.M.

AU - Joosten, M.H.A.J.

N1 - Mededeling 2002 - 26

PY - 2002

Y1 - 2002

N2 - Cladosporium fulvum is a semi-biotrophic pathogen, which causes leaf mold of tomato (Lycopersicon spp.). In our laboratory this pathosystem serves as a model to study gene-for-gene interactions between plants and pathogenic fungi (Joosten & De Wit 1999). Many avirulence (Avr) genes and matching resistance (Cf) genes have been cloned and we are now beginning to understand how their products can induce an array of plant defense responses, including the classic hypersensitive response (HR). Here, we will discuss the latest results of our molecular studies on this interaction. These include the isolation of: (i) two new Avr genes, Avr2 and Avr4E, (ii) the determination of the specificity determinants within the Cf-4 and Cf-9 genes by artificial domain swaps and introduction of point mutations, (iii) the analysis of polymorphism occurring in AVR9-responsive Cf genes occurring in natural populations of L. pimpinellifolium, and finally (iv) the description of an efficient method to identify early HR-related genes.

AB - Cladosporium fulvum is a semi-biotrophic pathogen, which causes leaf mold of tomato (Lycopersicon spp.). In our laboratory this pathosystem serves as a model to study gene-for-gene interactions between plants and pathogenic fungi (Joosten & De Wit 1999). Many avirulence (Avr) genes and matching resistance (Cf) genes have been cloned and we are now beginning to understand how their products can induce an array of plant defense responses, including the classic hypersensitive response (HR). Here, we will discuss the latest results of our molecular studies on this interaction. These include the isolation of: (i) two new Avr genes, Avr2 and Avr4E, (ii) the determination of the specificity determinants within the Cf-4 and Cf-9 genes by artificial domain swaps and introduction of point mutations, (iii) the analysis of polymorphism occurring in AVR9-responsive Cf genes occurring in natural populations of L. pimpinellifolium, and finally (iv) the description of an efficient method to identify early HR-related genes.

KW - cladosporium

KW - plantenziekteverwekkers

KW - solanum

KW - genetisch bepaalde resistentie

KW - overgevoeligheid

KW - cladosporium

KW - plant pathogens

KW - solanum

KW - genetic resistance

KW - hypersensitivity

U2 - 10.1023/A:1020553120889

DO - 10.1023/A:1020553120889

M3 - Article

SN - 0003-6072

VL - 81

SP - 409

EP - 412

JO - Antonie van Leeuwenhoek: Nederlandsch tijdschrift voor hygiëne, microbiologie en serologie

JF - Antonie van Leeuwenhoek: Nederlandsch tijdschrift voor hygiëne, microbiologie en serologie

IS - 1-4

ER -

The molecular basis of co-evolution between Cladosporium fulvum and tomato

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Keywords

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