The journey of resveratrol from yeast to human

Silvie Timmers; Johan Auwerx; Patrick Schrauwen

doi:10.18632/aging.100445

The journey of resveratrol from yeast to human

Silvie Timmers, Johan Auwerx, Patrick Schrauwen^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

150 Citations (Scopus)

Abstract

The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the recent years, this compound received renewed interest as several findings implicated resveratrol as a potent SIRT1 activator capable of mimicking the effects of calorie restriction, and regulating longevity in lower organisms. Given the worldwide increase in age-related metabolic diseases the beneficial effects of resveratrol on metabolism and healthy aging in humans are currently a topic of intense investigation.

Original language	English
Pages (from-to)	146-158
Number of pages	13
Journal	Aging
Volume	4
Issue number	3
DOIs	https://doi.org/10.18632/aging.100445
Publication status	Published - Mar 2012
Externally published	Yes

Keywords

Aging
Calorie restriction
Metabolic diseases
Resveratrol
SIRT1
Sirtuins

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10.18632/aging.100445Licence: CC BY

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KW - Calorie restriction

KW - Metabolic diseases

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KW - SIRT1

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The journey of resveratrol from yeast to human

Abstract

Keywords

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