The genomes of the livebearing fish species Poeciliopsis retropinna and Poeciliopsis turrubarensis reflect their different reproductive strategies

H. van Kruistum*, M.W. Guernsey, J.C. Baker, Susan L. Kloet, M.A.M. Groenen, B.J.A. Pollux*, H.J.W.C. Megens

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Abstract

The evolution of a placenta is predicted to be accompanied by rapid evolution of genes involved in processes that regulate mother–offspring interactions during pregnancy, such as placenta formation, embryonic development, and nutrient transfer to offspring. However, these predictions have only been tested in mammalian species, where only a single instance of placenta evolution has occurred. In this light, the genus Poeciliopsis is a particularly interesting model for placenta evolution, because in this genus a placenta has evolved independently from the mammalian placenta. Here, we present and compare genome assemblies of two species of the livebearing fish genus Poeciliopsis (family Poeciliidae) that differ in their reproductive strategy: Poeciliopsis retropinna which has a well-developed complex placenta and P. turrubarensis which lacks a placenta. We applied different assembly strategies for each species: PacBio sequencing for P. retropinna (622-Mb assembly, scaffold N50 of 21.6 Mb) and 10 Genomics Chromium technology for P. turrubarensis (597-Mb assembly, scaffold N50 of 4.2 Mb). Using the high contiguity of these genome assemblies and near-completeness of gene annotations to our advantage, we searched for gene duplications and performed a genome-wide scan for genes evolving under positive selection.We find rapid evolution inmajor parts of severalmolecular pathways involved in parent–offspring interaction in P. retropinna, both in the form of gene duplications as well as positive selection. We conclude that the evolution of the placenta in the genus Poeciliopsis is accompanied by rapid evolution of genes involved in similar genomic pathways as found in mammals.
Original languageEnglish
Pages (from-to)1376-1386
Number of pages15
JournalMolecular Biology and Evolution
Volume37
Issue number5
Early online date21 Jan 2020
DOIs
Publication statusPublished - May 2020

Fingerprint Dive into the research topics of 'The genomes of the livebearing fish species Poeciliopsis retropinna and Poeciliopsis turrubarensis reflect their different reproductive strategies'. Together they form a unique fingerprint.

Cite this