The Genome of the Fungal Pathogen Verticillium dahliae Reveals Extensive Bacterial to Fungal Gene Transfer

Xiaoqian Shi-Kunne, Mathijs van Kooten, Jasper R.L. Depotter, Bart P.H.J. Thomma*, Michael F. Seidl

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)

Abstract

Horizontal gene transfer (HGT) involves the transmission of genetic material between distinct evolutionary lineages and can be an important source of biological innovation. Reports of interkingdom HGT to eukaryotic microbial pathogens have accumulated over recent years. Verticillium dahliae is a notorious plant pathogen that causes vascular wilt disease on hundreds of plant species, resulting in high economic losses every year. Previously, the effector gene Ave1 and a glucosyltransferase-encoding gene were identified as virulence factor-encoding genes that were proposed to be horizontally acquired from a plant and a bacterial donor, respectively. However, to what extent HGT contributed to the overall genome composition of V. dahliae remained elusive. Here, we systematically searched for evidence of interkingdom HGT events in the genome of V. dahliae and provide evidence for extensive horizontal gene acquisition from bacterial origin.

Original languageEnglish
Pages (from-to)855-868
JournalGenome Biology and Evolution
Volume11
Issue number3
DOIs
Publication statusPublished - Mar 2019

Keywords

  • Verticillium
  • ascomycete
  • bacteria
  • fungus
  • horizontal gene transfer

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