The fungal biocontrol agent Coniothyrium minitans: production by solid-state fermentation, application and marketing

T. de Vrije, N. Antoine, R.M. Buitelaar, J. Oostra, A. Rinzema, F.J. Weber

Research output: Contribution to journalArticleAcademicpeer-review

94 Citations (Scopus)

Abstract

Biological control agents (BCAs) are potential alternatives for the chemical fungicides presently used in agriculture to fight plant diseases. Coniothyrium minitans is an example of a promising fungal BCA. It is a naturally occurring parasite of the fungus Sclerotinia sclerotiorum, a wide-spread pathogen which substantially reduces the yield of many crops. This review describes, exemplified by C. minitans, the studies that need to be carried out before a fungal BCA is successfully introduced into the market. The main aspects considered are the biology of C. minitans, the development of a product by mass production of spores using solid-state fermentation technology, its biocontrol activity and marketing of the final product.
Original languageEnglish
Pages (from-to)58-68
JournalApplied Microbiology and Biotechnology
Volume56
DOIs
Publication statusPublished - 2001

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