The effect of energy restriction on satiation an satiety in obese and lean men

W.A.M. Blom, A. Stafleu, H.F.J. Hendriks

Research output: Chapter in Book/Report/Conference proceedingConference paperAcademicpeer-review


Aims: To investigate how time-blinded obese and lean men compensate for a 3-day energy-restrictive diet. Methods: Subjects were randomly put on a three-day energy-restrictive (ER) (67% energy restriction) and a three-day energy-balanced (EB) diet, with a washout period of one month. Both diets were followed by a 24-hour time-blinded (overnight) stay at the research facility. In the morning, the subjects received breakfast and were told to ask for lunch if they felt hungry. When requested, subjects received an ad libitum lunch. Starting before breakfast till two hours after a meal request, measurements were taken at irregular time intervals. Transcriptomics, ghrelin and leptin data are still being processed. Results: Eleven obese (BMI 33.2 ± 0.8 kg/m2; age 40.8 ± 4.7 y) and nine lean (BMI 23.2 ± 0.5 kg/m2; age 33.2 ± 4.8 y) healthy men completed the study. The insulin response of the obese subjects after both meals was higher (p
Original languageEnglish
Title of host publication13th European Congress on Obesity, Prague, Czech Republic, 26-29 May 2004
PagesS214 (T7d:P7d-006)
Publication statusPublished - 2004


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