The control of feather pecking by serotonin

Y.M. van Hierden, S.F. de Boer, J.M. Koolhaas, S.M. Korte

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    Abstract

    Feather-pecking behavior in laying hens (Gallus gallus) may be considered a behavioral pathology, comparable to human psychopathological disorders. Scientific knowledge on the causation of such disorders strongly suggests involvement of the serotonergic (5-hydroxytryptamine; 5-HT) system in feather pecking. Previously, chicks from a high-feather-pecking (HFP) line were found to display lower 5-HT turnover levels than chicks from a low-feather-pecking (LFP) line (in response to acute stress; Y. M. van Hierden et al., 2002). The present study investigated whether low 5-HT neurotransmission modulates feather pecking. First, S-15535, a somatodendritic 5-HT1A autoreceptor agonist, was demonstrated to be an excellent tool for reducing 5-HT turnover in the forebrain of LFP and HFP chicks. Second, the most effective dose of S-15535 (4.0 mg/kg body weight) significantly increased severe feather-pecking behavior. The results confirmed the postulation that the performance of feather pecking is triggered by low 5-HT neurotransmission.
    Original languageEnglish
    Pages (from-to)575-583
    JournalBehavioral Neuroscience
    Volume118
    Issue number3
    DOIs
    Publication statusPublished - 2004

    Keywords

    • obsessive-compulsive disorder
    • laying hens
    • 5-ht1a autoreceptors
    • dopaminergic-neurons
    • (5-ht)(1a) receptors
    • manual restraint
    • s 15535
    • mice
    • modulation
    • turnover

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  • Cite this

    van Hierden, Y. M., de Boer, S. F., Koolhaas, J. M., & Korte, S. M. (2004). The control of feather pecking by serotonin. Behavioral Neuroscience, 118(3), 575-583. https://doi.org/10.1037/0735-7044.118.3.575