The application of DNA microarrays in gene expression analysis

N.L.W. van Hal, O. Vorst, A.M.M.L. van Houwelingen, E.J. Kok, A.A.C.M. Peijnenburg, A. Aharoni, A.J. van Tunen, J. Keijer

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)


DNA microarray technology is a new and powerful technology that will substantially increase the speed of molecular biological research. This paper gives a survey of DNA microarray technology and its use in gene expression studies. The technical aspects and their potential improvements are discussed. These comprise array manufacturing and design, array hybridisation, scanning, and data handling. Furthermore, it is discussed how DNA microarrays can be applied in the working fields of: safety, functionality and health of food and gene discovery and pathway engineering in plants.
Original languageEnglish
Pages (from-to)271-280
JournalJournal of Biotechnology
Issue number3
Publication statusPublished - 2000


  • DNA microarray technology
  • Food safety
  • Gene discovery
  • Gene expression
  • Pathway engineering
  • Review


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