The application of DNA microarrays in gene expression analysis

N.L.W. van Hal; O. Vorst; A.M.M.L. van Houwelingen; E.J. Kok; A.A.C.M. Peijnenburg; A. Aharoni; A.J. van Tunen; J. Keijer

doi:10.1016/S0168-1656(00)00204-2

The application of DNA microarrays in gene expression analysis

N.L.W. van Hal, O. Vorst, A.M.M.L. van Houwelingen, E.J. Kok, A.A.C.M. Peijnenburg, A. Aharoni, A.J. van Tunen, J. Keijer

Wageningen Food Safety Research

Research output: Contribution to journal › Article › Academic › peer-review

24 Citations (Scopus)

Abstract

DNA microarray technology is a new and powerful technology that will substantially increase the speed of molecular biological research. This paper gives a survey of DNA microarray technology and its use in gene expression studies. The technical aspects and their potential improvements are discussed. These comprise array manufacturing and design, array hybridisation, scanning, and data handling. Furthermore, it is discussed how DNA microarrays can be applied in the working fields of: safety, functionality and health of food and gene discovery and pathway engineering in plants.

Original language	English
Pages (from-to)	271-280
Journal	Journal of Biotechnology
Volume	78
Issue number	3
DOIs	https://doi.org/10.1016/S0168-1656(00)00204-2
Publication status	Published - 2000

Keywords

DNA microarray technology
Food safety
Gene discovery
Gene expression
Pathway engineering
Review

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10.1016/S0168-1656(00)00204-2

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title = "The application of DNA microarrays in gene expression analysis",

abstract = "DNA microarray technology is a new and powerful technology that will substantially increase the speed of molecular biological research. This paper gives a survey of DNA microarray technology and its use in gene expression studies. The technical aspects and their potential improvements are discussed. These comprise array manufacturing and design, array hybridisation, scanning, and data handling. Furthermore, it is discussed how DNA microarrays can be applied in the working fields of: safety, functionality and health of food and gene discovery and pathway engineering in plants.",

keywords = "DNA microarray technology, Food safety, Gene discovery, Gene expression, Pathway engineering, Review",

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T1 - The application of DNA microarrays in gene expression analysis

AU - van Hal, N.L.W.

AU - Vorst, O.

AU - van Houwelingen, A.M.M.L.

AU - Kok, E.J.

AU - Peijnenburg, A.A.C.M.

AU - Aharoni, A.

AU - van Tunen, A.J.

AU - Keijer, J.

PY - 2000

Y1 - 2000

N2 - DNA microarray technology is a new and powerful technology that will substantially increase the speed of molecular biological research. This paper gives a survey of DNA microarray technology and its use in gene expression studies. The technical aspects and their potential improvements are discussed. These comprise array manufacturing and design, array hybridisation, scanning, and data handling. Furthermore, it is discussed how DNA microarrays can be applied in the working fields of: safety, functionality and health of food and gene discovery and pathway engineering in plants.

AB - DNA microarray technology is a new and powerful technology that will substantially increase the speed of molecular biological research. This paper gives a survey of DNA microarray technology and its use in gene expression studies. The technical aspects and their potential improvements are discussed. These comprise array manufacturing and design, array hybridisation, scanning, and data handling. Furthermore, it is discussed how DNA microarrays can be applied in the working fields of: safety, functionality and health of food and gene discovery and pathway engineering in plants.

KW - DNA microarray technology

KW - Food safety

KW - Gene discovery

KW - Gene expression

KW - Pathway engineering

KW - Review

U2 - 10.1016/S0168-1656(00)00204-2

DO - 10.1016/S0168-1656(00)00204-2

M3 - Article

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VL - 78

SP - 271

EP - 280

JO - Journal of Biotechnology

JF - Journal of Biotechnology

IS - 3

ER -

The application of DNA microarrays in gene expression analysis

Abstract

Keywords

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