The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes

Kai Blin; Simon Shaw; Satria A. Kautsar; Marnix H. Medema; Tilmann Weber

doi:10.1093/nar/gkaa978

The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes

Kai Blin, Simon Shaw, Satria A. Kautsar, Marnix H. Medema, Tilmann Weber^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

93 Citations (Scopus)

Abstract

Microorganisms produce natural products that are frequently used in the development of antibacterial, antiviral, and anticancer drugs, pesticides, herbicides, or fungicides. In recent years, genome mining has evolved into a prominent method to access this potential. antiSMASH is one of the most popular tools for this task. Here, we present version 3 of the antiSMASH database, providing a means to access and query precomputed antiSMASH-5.2-detected biosynthetic gene clusters from representative, publicly available, high-quality microbial genomes via an interactive graphical user interface. In version 3, the database contains 147 517 high quality BGC regions from 388 archaeal, 25 236 bacterial and 177 fungal genomes and is available at https://antismash-db.secondarymetabolites.org/.

Original language	English
Pages (from-to)	D639-D643
Journal	Nucleic acids research
Volume	49
Issue number	D1
Early online date	5 Nov 2020
DOIs	https://doi.org/10.1093/nar/gkaa978
Publication status	Published - 8 Jan 2021

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The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes

Abstract

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