Synthesis of two hyaluronic-acid-related oligosaccharide 4-methoxyphenyl glycosides having a beta-D-glucuronic acid residue at the reducing end

Synthesis of two hyaluronic-acid-related oligosaccharides, the 4-methoxyphenyl β-glycosides of β-D-GlcpA-(1→3)-β-D-GlcpNAc-(1→4)-D-GlcpA and β-D-GlcpA-(1→3)-β-D-GlcpNAc-(1→4)-β-D-GlcpA-(1→3)- β-D-GJcpNAc-(1→4)-D-GlcpA, is described. D-Glucopyranosyluronic acid residues were obtained by selective oxidation at C6 of corresponding D-glucopyranosyl residues after construction of the oligosaccharide backbones, using pyridinium dichromate and acetic anhydride.