Synthesis of [7,7-H-2(2)]epibrassinolide

V.A. Khripach, N.B. Khripach, V.N. Zhabinskii, Y.Y. Zhiburtovich, B. Schneider, Æ. de Groot

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7 Citations (Scopus)


Synthesis of labelled epibrassinolide containing two deuterium atoms in a position which is not subjected to isotopic exchange is reported. Key transformations include preparation of 6,7-seco steroidal diacid, its cyclization to a cyclic anhydride followed by a regioselective reduction with NaBD4. The obtained [7,7-2H2]epibrassinolide can be used in biochemical experiments when the loss of isotopic label should be avoided
Original languageEnglish
Pages (from-to)1153-1158
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Issue number13-14
Publication statusPublished - 2007


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