syntenet: an R/Bioconductor package for the inference and analysis of synteny networks

Fabricio Almeida-Silva, Tao Zhao, Kristian K. Ullrich, M.E. Schranz, Yves Van de Peer*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Interpreting and visualizing synteny relationships across several genomes is a challenging task. We previously proposed a network-based approach for better visualization and interpretation of large-scale microsynteny analyses. Here, we present syntenet, an R package to infer and analyze synteny networks from whole-genome protein sequence data. The package offers a simple and complete framework, including data preprocessing, synteny detection and network inference, network clustering and phylogenomic profiling, and microsynteny-based phylogeny inference. Graphical functions are also available to create publication-ready plots. Synteny networks inferred with syntenet can highlight taxon-specific gene clusters that likely contributed to the evolution of important traits, and microsynteny-based phylogenies can help resolve phylogenetic relationships under debate.
Original languageEnglish
Article numberbtac806
Issue number1
Publication statusPublished - 22 Dec 2022


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