Subgrouping of bovine respiratory syncytial virus strains detected in lung tissue

R.S. Schrijver, E. Daus, J.A. Kramps, J.P.M. Langedijk, R. Buijs, W.G.J. Middel, G. Taylor, J. Furze, M.W.C. Huyben, J.T. van Oirschot

    Research output: Contribution to journalArticleAcademicpeer-review

    32 Citations (Scopus)

    Abstract

    Bovine respiratory syncytial virus is an important respiratory pathogen in cattle. Recently, subgroups of BRSV have been identified, based on antigenic differences. However, little is known about subgroups of BRSV that circulate in the cattle population. Therefore, we determined the reactivity of monoclonal antibodies (mAbs), directed against the G, F, or P protein of BRSV, with lung tissue from 47 calves, that suffered from severe respiratory disease. Fourteen animals (30%) proved to be infected with BRSV, because they all reacted with mAbs against the P or F protein, as detected by fluorescent antibody tests. Monoclonal antibodies against the G protein were abl
    Original languageEnglish
    Pages (from-to)253-260
    JournalVeterinary Microbiology
    Volume53
    Issue number3-4
    DOIs
    Publication statusPublished - 1996

    Keywords

    • Bovine respiratory syncytial virus
    • Cattle-viruses
    • Monoclonal antibodies

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