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Abstract
The great tit (Parus major) is a songbird that has been extensively explored in ecological and evolutionary studies, shedding light on the effects of the global warming on nature. Genomic structural variability was never explored in detail in these species. The aim of this thesis was to detect, map, characterize and associate, with seasonal timing, structural variants that are present in the great tit genome such as copy number variations (CNVs) and inversions. First, this thesis presents a genome-wide map of CNV regions in the great tit genome, showing how these variants are associated with genomic architecture underlying their molecular formation. Second, CNVs were associated with breeding timing. Finally, this thesis investigate the genomic complexity of a large inversion in the Chromosome 1A. The inversion is recessive lethal and is inherited twice more than expected from male carriers but are normally inherited from female carriers, suggesting a selfish gene.
Original language | English |
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Qualification | Doctor of Philosophy |
Awarding Institution |
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Supervisors/Advisors |
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Award date | 24 Jan 2020 |
Place of Publication | Wageningen |
Publisher | |
Print ISBNs | 9789177605201 |
DOIs | |
Publication status | Published - 24 Jan 2020 |
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Dive into the research topics of 'Structural variants in the great tit genome and their effect on seasonal timing'. Together they form a unique fingerprint.Projects
- 1 Finished
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Genetic research on songbirds
da Silva, V. (PhD candidate), Groenen, M. A. M. (Promotor) & Crooijmans, R. (Co-promotor)
1/09/15 → 24/01/20
Project: PhD