Strong inhibition of cholera toxin binding by galactose dendrimers

H.M. Branderhorst, R.M.J. Liskamp, G.M. Visser, R.J. Pieters

Research output: Contribution to journalArticleAcademicpeer-review

68 Citations (Scopus)

Abstract

Galactose-containing dendrimers with long spacer arms inhibit cholera toxin binding as strongly as the natural ganglioside GM1 oligosaccharide does.
Original languageEnglish
Pages (from-to)5043-5045
JournalChemical Communications
Issue number47
DOIs
Publication statusPublished - 2007

Keywords

  • heat-labile enterotoxin
  • terminal alkynes
  • solid-phase
  • b-subunit
  • gm1
  • ligand
  • oligosaccharide
  • cycloaddition
  • design
  • azides

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