Stimulation of cholesterol biosynthesis in mitochondrial complex I-deficiency lowers reductive stress and improves motor function and survival in mice

Tom J.J. Schirris, Sergio Rossell, Ria de Haas, Sanne J.C.M. Frambach, Charlotte A. Hoogstraten, Herma Renkema, Julien D. Beyrath, Peter H.G.M. Willems, Martijn A. Huynen, Jan A.M. Smeitink, Frans G.M. Russel*, Richard A. Notebaart

*Corresponding author for this work

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Medicine & Life Sciences