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Stimulation of cholesterol biosynthesis in mitochondrial complex I-deficiency lowers reductive stress and improves motor function and survival in mice

  • Tom J.J. Schirris
  • , Sergio Rossell
  • , Ria de Haas
  • , Sanne J.C.M. Frambach
  • , Charlotte A. Hoogstraten
  • , Herma Renkema
  • , Julien D. Beyrath
  • , Peter H.G.M. Willems
  • , Martijn A. Huynen
  • , Jan A.M. Smeitink
  • , Frans G.M. Russel*
  • , Richard A. Notebaart*
  • *Corresponding author for this work

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