Sphere size distributions from finite thickness sections: a forward approach employing a genetic algorithm

S. de Nooijer, M.J. Ketelaar, B. Mulder

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We formulate, implement and test a robust method of determining sphere size distributions from finite thickness planar sections. The method uses a forward approach in which populations of proposed distributions are tested against the input data and refined using a genetic algorithm. This method is then applied to a real-world data set concerning endo- and exocytotic vesicles in the apical region of tip growing pollen tubes of Arabidopsis thaliana.
Original languageEnglish
Pages (from-to)257-264
JournalJournal of Microscopy
Issue number2
Publication statusPublished - 2008



  • particle-size
  • pathological research
  • numerical evaluation
  • electron-microscopy
  • projections
  • diagnosis
  • objects

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