Abstract
The toxicity of fine chemicals to the producer organism is a problem in several biotechnological production processes. In several instances, an organic phase can be used to extract the toxic product from the aqueous phase during a fermentation. With the discovery of solvent-tolerant bacteria, more solvents can now be used in such two-liquid water-solvent systems. We are gaining new insights into the mechanisms of bacterial solvent tolerance, such as the active efflux of solvents from the cytoplasmic membrane and solvent-impermeable outer membranes.
| Original language | English |
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| Pages (from-to) | 493-499 |
| Journal | Trends in Biotechnology |
| Volume | 16 |
| DOIs | |
| Publication status | Published - 1998 |