Site-specific intestinal delivery and/or production of biologically active substances

P.A. Bron; W.M. de Vos; M. Kleerebezem

Site-specific intestinal delivery and/or production of biologically active substances

P.A. Bron (Inventor), W.M. de Vos (Inventor), M. Kleerebezem (Inventor)

Research output: Patent

Abstract

The present invention relates to the site-specific production of biologically active substances by recombinant micro-organisms in body cavities of a human or animal subject. The invention provides transcription regulatory sequences, which are specifically induced in the gastrointestinal tract (GI-tract) of subjects and methods for their use for in vivo site-specific expression of nucleic acid sequences encoding biologically active substances.

Original language	English
Patent number	WO2005040387
Publication status	Published - 6 May 2005

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title = "Site-specific intestinal delivery and/or production of biologically active substances",

abstract = "The present invention relates to the site-specific production of biologically active substances by recombinant micro-organisms in body cavities of a human or animal subject. The invention provides transcription regulatory sequences, which are specifically induced in the gastrointestinal tract (GI-tract) of subjects and methods for their use for in vivo site-specific expression of nucleic acid sequences encoding biologically active substances.",

author = "P.A. Bron and {de Vos}, W.M. and M. Kleerebezem",

year = "2005",

month = may,

day = "6",

language = "English",

type = "Patent",

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TY - PAT

T1 - Site-specific intestinal delivery and/or production of biologically active substances

AU - Bron, P.A.

AU - de Vos, W.M.

AU - Kleerebezem, M.

PY - 2005/5/6

Y1 - 2005/5/6

N2 - The present invention relates to the site-specific production of biologically active substances by recombinant micro-organisms in body cavities of a human or animal subject. The invention provides transcription regulatory sequences, which are specifically induced in the gastrointestinal tract (GI-tract) of subjects and methods for their use for in vivo site-specific expression of nucleic acid sequences encoding biologically active substances.

AB - The present invention relates to the site-specific production of biologically active substances by recombinant micro-organisms in body cavities of a human or animal subject. The invention provides transcription regulatory sequences, which are specifically induced in the gastrointestinal tract (GI-tract) of subjects and methods for their use for in vivo site-specific expression of nucleic acid sequences encoding biologically active substances.

M3 - Patent

M1 - WO2005040387

ER -

Site-specific intestinal delivery and/or production of biologically active substances

Abstract

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