Site-specific intestinal delivery and/or production of biologically active substances

P.A. Bron (Inventor), W.M. de Vos (Inventor), M. Kleerebezem (Inventor)

Research output: PatentOther research output

Abstract

The present invention relates to the site-specific production of biologically active substances by recombinant micro-organisms in body cavities of a human or animal subject. The invention provides transcription regulatory sequences, which are specifically induced in the gastrointestinal tract (GI-tract) of subjects and methods for their use for in vivo site-specific expression of nucleic acid sequences encoding biologically active substances.
Original languageEnglish
Patent numberWO2005040387
Publication statusPublished - 6 May 2005

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Nucleic Acids
Gastrointestinal Tract

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abstract = "The present invention relates to the site-specific production of biologically active substances by recombinant micro-organisms in body cavities of a human or animal subject. The invention provides transcription regulatory sequences, which are specifically induced in the gastrointestinal tract (GI-tract) of subjects and methods for their use for in vivo site-specific expression of nucleic acid sequences encoding biologically active substances.",
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Site-specific intestinal delivery and/or production of biologically active substances. / Bron, P.A. (Inventor); de Vos, W.M. (Inventor); Kleerebezem, M. (Inventor).

Patent No.: WO2005040387.

Research output: PatentOther research output

TY - PAT

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AU - Kleerebezem, M.

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AB - The present invention relates to the site-specific production of biologically active substances by recombinant micro-organisms in body cavities of a human or animal subject. The invention provides transcription regulatory sequences, which are specifically induced in the gastrointestinal tract (GI-tract) of subjects and methods for their use for in vivo site-specific expression of nucleic acid sequences encoding biologically active substances.

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