Abstract
In vivo studies of human mucosal gut microbiota are often limited to end-point analyses and confounded by bowel cleansing procedures. Therefore, we used biofilm reactors to incorporate a simulated mucosal environment into an in vitro gut chemostat model. Communities developed were complex, reproducible, distinct, and representative of in vivo communities.
Original language | English |
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Pages (from-to) | 36-44 |
Journal | Journal of Microbiological Methods |
Volume | 108 |
DOIs | |
Publication status | Published - 2015 |
Keywords
- human intestinal microbiota
- motile bacteria
- clindamycin
- mucin
- diversity
- colonization
- resistance
- stability
- system
- akkermansia