Silent memory induction in maternal immune young animals

W.J.A. Boersma, E.M.A. van Rooij, J.W. Scholten, R.J. Zwart, T.G. Kimman, A. Bianchi

    Research output: Contribution to journalArticleAcademicpeer-review

    9 Citations (Scopus)


    Maternal immunity was shown to be an effector mechanism which does not include transfer of memory. 'Boosting' of maternal immunity by vaccination was not effective. Transferred maternal immunity negatively interfered with the induction of optimal protection by vaccination. Antibody formation was not observed after vaccination of maternally immune piglets. In contrast, induction of memory had occurred in animals under maternal immune suppression. Vaccination in young animals negatively interfered with or abrogated, effective maternal immune protection. There was no correlation between specific serum antibody titres in piglets and protection to PRV. Thus apart from protection provided by antibodies contributions of other soluble factors and the cellular immune compartment as represented in colostrum and/or milk were important for protection.
    Original languageEnglish
    Pages (from-to)S89-S92
    JournalVeterinary Quarterly
    Issue numberSUPPL. 3
    Publication statusPublished - 1998


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