Signatures of Diversifying Selection in European Pig Breeds

S. Wilkinson, Z.H. Lu, H.J.W.C. Megens, A.L. Archibald, C. Haley, I.J. Jackson, M.A.M. Groenen, R.P.M.A. Crooijmans, R. Ogden, P. Wiener

Research output: Contribution to journalArticleAcademicpeer-review

115 Citations (Scopus)

Abstract

Following domestication, livestock breeds have experienced intense selection pressures for the development of desirable traits. This has resulted in a large diversity of breeds that display variation in many phenotypic traits, such as coat colour, muscle composition, early maturity, growth rate, body size, reproduction, and behaviour. To better understand the relationship between genomic composition and phenotypic diversity arising from breed development, the genomes of 13 traditional and commercial European pig breeds were scanned for signatures of diversifying selection using the Porcine60K SNP chip, applying a between-population (differentiation) approach. Signatures of diversifying selection between breeds were found in genomic regions associated with traits related to breed standard criteria, such as coat colour and ear morphology. Amino acid differences in the EDNRB gene appear to be associated with one of these signatures, and variation in the KITLG gene may be associated with another. Other selection signals were found in genomic regions including QTLs and genes associated with production traits such as reproduction, growth, and fat deposition. Some selection signatures were associated with regions showing evidence of introgression from Asian breeds. When the European breeds were compared with wild boar, genomic regions with high levels of differentiation harboured genes related to bone formation, growth, and fat deposition.
Original languageEnglish
Article numbere1003453
JournalPlos Genetics
Volume9
Issue number4
DOIs
Publication statusPublished - 2013

Keywords

  • quantitative trait loci
  • fatty-acid-composition
  • coat color
  • artificial selection
  • kit-ligand
  • skin pigmentation
  • complex traits
  • teat number
  • wild boar
  • ear size

Fingerprint Dive into the research topics of 'Signatures of Diversifying Selection in European Pig Breeds'. Together they form a unique fingerprint.

Cite this