Selectivity of lipases for estolides synthesis

Anamaria Todea; A.E. Frissen; Linda G. Otten; I. Arends; F. Peter; C.G. Boeriu

doi:10.1515/pac-2014-0716

Selectivity of lipases for estolides synthesis

Anamaria Todea, A.E. Frissen, Linda G. Otten, I. Arends, F. Peter, C.G. Boeriu^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Abstract

Lipase-catalyzed synthesis of estolides starting from different saturated (C16 16OH, C18 12OH) and unsaturated (C18:1 9 cis 12-OH) hydroxy-fatty acids was investigated. For this reason, the catalytic efficiency of several native and immobilized lipases in different organic reaction media at temperatures up to 75 °C was studied. The formation of mono- and di-lactone as well as estolide’s chain elongation depends on the type and source of lipase. The lipase from Pseudomonas stutzeri immobilized by cross-linking as cross-linked enzymes aggregates (CLEAs) was the best biocatalyst in terms of chain elongation. Estolides with polymerization degree up to 10 were obtained at substrate conversions higher than 80 %.

Original language	English
Pages (from-to)	51-58
Journal	Pure and Applied Chemistry
Volume	87
Issue number	1
DOIs	https://doi.org/10.1515/pac-2014-0716
Publication status	Published - 2015

Keywords

Estolide
Hydroxy fatty acid
Lipase
POC-2014
Selectivity

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title = "Selectivity of lipases for estolides synthesis",

abstract = "Lipase-catalyzed synthesis of estolides starting from different saturated (C16 16OH, C18 12OH) and unsaturated (C18:1 9 cis 12-OH) hydroxy-fatty acids was investigated. For this reason, the catalytic efficiency of several native and immobilized lipases in different organic reaction media at temperatures up to 75 °C was studied. The formation of mono- and di-lactone as well as estolide{\textquoteright}s chain elongation depends on the type and source of lipase. The lipase from Pseudomonas stutzeri immobilized by cross-linking as cross-linked enzymes aggregates (CLEAs) was the best biocatalyst in terms of chain elongation. Estolides with polymerization degree up to 10 were obtained at substrate conversions higher than 80 %.",

keywords = "Estolide, Hydroxy fatty acid, Lipase, POC-2014, Selectivity",

author = "Anamaria Todea and A.E. Frissen and Otten, {Linda G.} and I. Arends and F. Peter and C.G. Boeriu",

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T1 - Selectivity of lipases for estolides synthesis

AU - Todea, Anamaria

AU - Frissen, A.E.

AU - Otten, Linda G.

AU - Arends, I.

AU - Peter, F.

AU - Boeriu, C.G.

PY - 2015

Y1 - 2015

N2 - Lipase-catalyzed synthesis of estolides starting from different saturated (C16 16OH, C18 12OH) and unsaturated (C18:1 9 cis 12-OH) hydroxy-fatty acids was investigated. For this reason, the catalytic efficiency of several native and immobilized lipases in different organic reaction media at temperatures up to 75 °C was studied. The formation of mono- and di-lactone as well as estolide’s chain elongation depends on the type and source of lipase. The lipase from Pseudomonas stutzeri immobilized by cross-linking as cross-linked enzymes aggregates (CLEAs) was the best biocatalyst in terms of chain elongation. Estolides with polymerization degree up to 10 were obtained at substrate conversions higher than 80 %.

AB - Lipase-catalyzed synthesis of estolides starting from different saturated (C16 16OH, C18 12OH) and unsaturated (C18:1 9 cis 12-OH) hydroxy-fatty acids was investigated. For this reason, the catalytic efficiency of several native and immobilized lipases in different organic reaction media at temperatures up to 75 °C was studied. The formation of mono- and di-lactone as well as estolide’s chain elongation depends on the type and source of lipase. The lipase from Pseudomonas stutzeri immobilized by cross-linking as cross-linked enzymes aggregates (CLEAs) was the best biocatalyst in terms of chain elongation. Estolides with polymerization degree up to 10 were obtained at substrate conversions higher than 80 %.

KW - Estolide

KW - Hydroxy fatty acid

KW - Lipase

KW - POC-2014

KW - Selectivity

U2 - 10.1515/pac-2014-0716

DO - 10.1515/pac-2014-0716

M3 - Article

VL - 87

SP - 51

EP - 58

JO - Pure and Applied Chemistry

JF - Pure and Applied Chemistry

SN - 0033-4545

IS - 1

ER -

Selectivity of lipases for estolides synthesis

Abstract

Keywords

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