Selective Production of Maleic Acid from Furfural via a Cascade Approach Combining Photochemistry and Electro- or Biochemistry

Shanmugam Thiyagarajan; David Franciolus; Roel J.M. Bisselink; Tom A. Ewing; Carmen G. Boeriu; Jacco Van Haveren

doi:10.1021/acssuschemeng.0c02833

Selective Production of Maleic Acid from Furfural via a Cascade Approach Combining Photochemistry and Electro- or Biochemistry

Shanmugam Thiyagarajan^*, David Franciolus, Roel J.M. Bisselink, Tom A. Ewing, Carmen G. Boeriu, Jacco Van Haveren

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

20 Citations (Scopus)

Abstract

Starting from furfural, maleic acid is efficiently synthesized in two steps under very mild conditions. In the first step, 5-hydroxy-2(5H)-furanone is synthesized via photochemical oxidation and proposed as a stable intermediate. Subsequent oxidation in the second step, by either an electrochemical or enzymatic process, results in maleic acid in high yield and selectivity.

Original language	English
Pages (from-to)	10626–10632
Journal	ACS sustainable chemistry & engineering
Volume	8
Issue number	29
DOIs	https://doi.org/10.1021/acssuschemeng.0c02833
Publication status	Published - 7 Jul 2020

Keywords

Electrochemical oxidation
Enzymatic oxidation
Maleic acid
Nitroxyl radicals
TEMPO

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/acssuschemeng.0c02833Licence: CC BY-NC-ND

https://edepot.wur.nl/528825Licence: CC BY-NC-ND

Cite this

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title = "Selective Production of Maleic Acid from Furfural via a Cascade Approach Combining Photochemistry and Electro- or Biochemistry",

abstract = "Starting from furfural, maleic acid is efficiently synthesized in two steps under very mild conditions. In the first step, 5-hydroxy-2(5H)-furanone is synthesized via photochemical oxidation and proposed as a stable intermediate. Subsequent oxidation in the second step, by either an electrochemical or enzymatic process, results in maleic acid in high yield and selectivity.",

keywords = "Electrochemical oxidation, Enzymatic oxidation, Maleic acid, Nitroxyl radicals, TEMPO",

author = "Shanmugam Thiyagarajan and David Franciolus and Bisselink, {Roel J.M.} and Ewing, {Tom A.} and Boeriu, {Carmen G.} and {Van Haveren}, Jacco",

year = "2020",

month = jul,

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doi = "10.1021/acssuschemeng.0c02833",

language = "English",

volume = "8",

pages = "10626–10632",

journal = "ACS sustainable chemistry & engineering",

issn = "2168-0485",

publisher = "American Chemical Society",

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Selective Production of Maleic Acid from Furfural via a Cascade Approach Combining Photochemistry and Electro- or Biochemistry. / Thiyagarajan, Shanmugam; Franciolus, David; Bisselink, Roel J.M. et al.
In: ACS sustainable chemistry & engineering, Vol. 8, No. 29, 07.07.2020, p. 10626–10632.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Selective Production of Maleic Acid from Furfural via a Cascade Approach Combining Photochemistry and Electro- or Biochemistry

AU - Thiyagarajan, Shanmugam

AU - Franciolus, David

AU - Bisselink, Roel J.M.

AU - Ewing, Tom A.

AU - Boeriu, Carmen G.

AU - Van Haveren, Jacco

PY - 2020/7/7

Y1 - 2020/7/7

N2 - Starting from furfural, maleic acid is efficiently synthesized in two steps under very mild conditions. In the first step, 5-hydroxy-2(5H)-furanone is synthesized via photochemical oxidation and proposed as a stable intermediate. Subsequent oxidation in the second step, by either an electrochemical or enzymatic process, results in maleic acid in high yield and selectivity.

AB - Starting from furfural, maleic acid is efficiently synthesized in two steps under very mild conditions. In the first step, 5-hydroxy-2(5H)-furanone is synthesized via photochemical oxidation and proposed as a stable intermediate. Subsequent oxidation in the second step, by either an electrochemical or enzymatic process, results in maleic acid in high yield and selectivity.

KW - Electrochemical oxidation

KW - Enzymatic oxidation

KW - Maleic acid

KW - Nitroxyl radicals

KW - TEMPO

U2 - 10.1021/acssuschemeng.0c02833

DO - 10.1021/acssuschemeng.0c02833

M3 - Article

SN - 2168-0485

VL - 8

SP - 10626

EP - 10632

JO - ACS sustainable chemistry & engineering

JF - ACS sustainable chemistry & engineering

IS - 29

ER -

Selective Production of Maleic Acid from Furfural via a Cascade Approach Combining Photochemistry and Electro- or Biochemistry

Abstract

Keywords

UN SDGs

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