Selective Oxidative Decarboxylation of Amino Acids to Produce Industrially Relevant Nitriles by Vanadium Chloroperoxidase

A. But, J.E.L. le Notre, E.L. Scott, R. Wever, J.P.M. Sanders

Research output: Contribution to journalArticleAcademicpeer-review

35 Citations (Scopus)

Abstract

Industrial nitriles from biomass: Vanadium-chloroperoxidase is successfully used to transform selectively glutamic acid into 3-cyanopropanoic acid, a key intermediate for the synthesis of bio-succinonitrile and bio-acrylonitrile, by using a catalytic amount of a halide salt. This clean oxidative decarboxylation can be applied to mixtures of amino acids obtained from plant waste streams, leading to easily separable nitriles.
Original languageEnglish
Pages (from-to)1199-1202
JournalChemSusChem
Volume5
Issue number7
DOIs
Publication statusPublished - 2012

Keywords

  • fungus curvularia-inaequalis
  • renewable chemicals
  • glutamic-acid
  • biomass
  • bromoperoxidase
  • bromination
  • conversion
  • enzyme

Fingerprint Dive into the research topics of 'Selective Oxidative Decarboxylation of Amino Acids to Produce Industrially Relevant Nitriles by Vanadium Chloroperoxidase'. Together they form a unique fingerprint.

  • Cite this