Selective enzymatic hydrolysis of C-terminal tert-butyl esters of peptides

I.F. Eggen; C.G. Boeriu

Selective enzymatic hydrolysis of C-terminal tert-butyl esters of peptides

I.F. Eggen (Inventor)
, C.G. Boeriu (Inventor)

Research output: Patent

Abstract

The present invention relates to a process for the selective enzymatic hydrolysis of C-terminal esters of peptide substrates in the synthesis of peptides, comprising hydrolysing C-terminal tert-butyl esters using the protease subtilisin. This process is useful in the production of protected or unprotected peptides.

Original language	English
Patent number	WO2007082890
Priority date	17/01/06
Publication status	Published - 26 Jul 2007

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title = "Selective enzymatic hydrolysis of C-terminal tert-butyl esters of peptides",

abstract = "The present invention relates to a process for the selective enzymatic hydrolysis of C-terminal esters of peptide substrates in the synthesis of peptides, comprising hydrolysing C-terminal tert-butyl esters using the protease subtilisin. This process is useful in the production of protected or unprotected peptides.",

author = "I.F. Eggen and C.G. Boeriu",

year = "2007",

month = jul,

day = "26",

language = "English",

type = "Patent",

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T1 - Selective enzymatic hydrolysis of C-terminal tert-butyl esters of peptides

AU - Eggen, I.F.

AU - Boeriu, C.G.

PY - 2007/7/26

Y1 - 2007/7/26

N2 - The present invention relates to a process for the selective enzymatic hydrolysis of C-terminal esters of peptide substrates in the synthesis of peptides, comprising hydrolysing C-terminal tert-butyl esters using the protease subtilisin. This process is useful in the production of protected or unprotected peptides.

AB - The present invention relates to a process for the selective enzymatic hydrolysis of C-terminal esters of peptide substrates in the synthesis of peptides, comprising hydrolysing C-terminal tert-butyl esters using the protease subtilisin. This process is useful in the production of protected or unprotected peptides.

M3 - Patent

M1 - WO2007082890

ER -

Selective enzymatic hydrolysis of C-terminal tert-butyl esters of peptides

Abstract

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