Secreted venom allergen-like proteins of plant-parasitic nematodes modulate defence responses in host plants

Research output: Chapter in Book/Report/Conference proceedingAbstract

Abstract

The venom allergen-like proteins form a family of effectors that seems to be conserved among all parasitic nematodes of plants and animals studied to date. Recently, we have shown that the venom allergen-like protein of the potato cyst nematode Globodera rostochiensis Gr-VAP1 interacts with the apoplastic cysteine papain-like proteases Rcr3pim of Solanum pimpinellifolium. Gr-VAP1 and Rcr3pim are both required to activate defence-related programmed cell death and resistance to nematodes mediated by the extracellular plant immune receptor Cf-2 in tomato. Thus, Gr-VAP1 is able to trigger defence responses in a host plant of G. rostochiensis, but the virulence function of Gr-VAP1 or of any other venom allergen-like protein of an animal-and plant-parasitic nematode is not known. A specific knock-down of Gr-VAP1 expression in G. rostochiensis showed that the effector is indeed important for virulence of infective juveniles in host plants. Similarly, the ectopic expression of venom allergen-like proteins in transgenic plants alters their response to nematodes and other plant pathogens. Transcriptopme analysis of these transgenic plants has shed light on the molecular mechanisms underlying the virulence function of venom allergen-like protein of plant-parasitic nematodes in plants
Original languageEnglish
Title of host publicationProceedings of the 6th International Congress of Nematology, 4-9 May 2014, Cape Town, South Africa
Pages72-72
Publication statusPublished - 2014
Event6th International Congress of Nematology, Cape Town, South Africa -
Duration: 4 May 20149 May 2014

Conference

Conference6th International Congress of Nematology, Cape Town, South Africa
Period4/05/149/05/14

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