Screening of selective androgen receptor modulators by hand-held laser diode thermal desorption-transportable mass spectrometry

A. Arrizabalaga Larrañaga; M.H. Blokland; M.W.F. Nielen

Screening of selective androgen receptor modulators by hand-held laser diode thermal desorption-transportable mass spectrometry

A. Arrizabalaga Larrañaga, M.H. Blokland, M.W.F. Nielen

Research output: Contribution to conference › Poster › Academic

Abstract

Rapid and easy-to-perform (on-site) analysis methods have a bright future in forensic and food analysis. Implementing on-site prescreening of target compounds in samples would reduce the number of suspicious samples to be transported to the control laboratories for their analysis. Therefore, it would improve the efficiency of control and monitoring programs.
Ambient ionization mass spectrometry (AIMS) techniques offer simplified sample preparation and sample introduction protocols. However, today, only a few studies reported ambient ionization of food contaminants and drug analysis with a (trans)portable MS system. This work developed a handheld laser diode thermal desorption electrospray ionization (LDTD-ESI) mass spectrometry method to
rapidly screen illegal substances in solid samples. The applicability was demonstrated to rapidly identify selective androgen receptor modulators (SARMs) in powders and pills [1].

Original language	English
Number of pages	1
Publication status	Published - 23 May 2022
Event	EuroResidue Conference IX 2022 - Hotel de Ruwenberg, St. Michielsgestel, Netherlands Duration: 23 May 2022 → 25 May 2022 https://www.euroresidue.eu/

Conference

Conference	EuroResidue Conference IX 2022
Country/Territory	Netherlands
City	St. Michielsgestel
Period	23/05/22 → 25/05/22
Internet address	https://www.euroresidue.eu/

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https://edepot.wur.nl/571765Licence: Publisher

1 Finished
1 Active

Speerpunt 2 - Detecteren (KB-37-002-037)
Blokland, M.
1/01/22 → 31/12/23
Project: EZproject
Risico's nanotechnologie biobeschikbaarheid en toxicologie contrafinanciering (KB-37-002-001, KB-23-002-005, KB-15-003-010)
Peters, R.
1/01/11 → 31/12/21
Project: EZproject

Cite this

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title = "Screening of selective androgen receptor modulators by hand-held laser diode thermal desorption-transportable mass spectrometry",

abstract = "Rapid and easy-to-perform (on-site) analysis methods have a bright future in forensic and food analysis. Implementing on-site prescreening of target compounds in samples would reduce the number of suspicious samples to be transported to the control laboratories for their analysis. Therefore, it would improve the efficiency of control and monitoring programs.Ambient ionization mass spectrometry (AIMS) techniques offer simplified sample preparation and sample introduction protocols. However, today, only a few studies reported ambient ionization of food contaminants and drug analysis with a (trans)portable MS system. This work developed a handheld laser diode thermal desorption electrospray ionization (LDTD-ESI) mass spectrometry method torapidly screen illegal substances in solid samples. The applicability was demonstrated to rapidly identify selective androgen receptor modulators (SARMs) in powders and pills [1].",

author = "{Arrizabalaga Larra{\~n}aga}, A. and M.H. Blokland and M.W.F. Nielen",

year = "2022",

month = may,

day = "23",

language = "English",

note = "EuroResidue Conference IX 2022 ; Conference date: 23-05-2022 Through 25-05-2022",

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TY - CONF

T1 - Screening of selective androgen receptor modulators by hand-held laser diode thermal desorption-transportable mass spectrometry

AU - Arrizabalaga Larrañaga, A.

AU - Blokland, M.H.

AU - Nielen, M.W.F.

PY - 2022/5/23

Y1 - 2022/5/23

N2 - Rapid and easy-to-perform (on-site) analysis methods have a bright future in forensic and food analysis. Implementing on-site prescreening of target compounds in samples would reduce the number of suspicious samples to be transported to the control laboratories for their analysis. Therefore, it would improve the efficiency of control and monitoring programs.Ambient ionization mass spectrometry (AIMS) techniques offer simplified sample preparation and sample introduction protocols. However, today, only a few studies reported ambient ionization of food contaminants and drug analysis with a (trans)portable MS system. This work developed a handheld laser diode thermal desorption electrospray ionization (LDTD-ESI) mass spectrometry method torapidly screen illegal substances in solid samples. The applicability was demonstrated to rapidly identify selective androgen receptor modulators (SARMs) in powders and pills [1].

AB - Rapid and easy-to-perform (on-site) analysis methods have a bright future in forensic and food analysis. Implementing on-site prescreening of target compounds in samples would reduce the number of suspicious samples to be transported to the control laboratories for their analysis. Therefore, it would improve the efficiency of control and monitoring programs.Ambient ionization mass spectrometry (AIMS) techniques offer simplified sample preparation and sample introduction protocols. However, today, only a few studies reported ambient ionization of food contaminants and drug analysis with a (trans)portable MS system. This work developed a handheld laser diode thermal desorption electrospray ionization (LDTD-ESI) mass spectrometry method torapidly screen illegal substances in solid samples. The applicability was demonstrated to rapidly identify selective androgen receptor modulators (SARMs) in powders and pills [1].

M3 - Poster

T2 - EuroResidue Conference IX 2022

Y2 - 23 May 2022 through 25 May 2022

ER -

Screening of selective androgen receptor modulators by hand-held laser diode thermal desorption-transportable mass spectrometry

Abstract

Conference

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Projects

Speerpunt 2 - Detecteren (KB-37-002-037)

Risico's nanotechnologie biobeschikbaarheid en toxicologie contrafinanciering (KB-37-002-001, KB-23-002-005, KB-15-003-010)

Cite this